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DMFT 指数与 HIV 感染相关的口腔黏膜病变:巴西亚马逊地区波多韦柳横断面研究。

DMFT index and oral mucosal lesions associated with HIV infection: cross-sectional study in Porto Velho, Amazonian region - Brazil.

机构信息

Faculdade São Lucas, Instituto Básico de Biociências, Unitau.

出版信息

Braz J Infect Dis. 2010 Sep-Oct;14(5):449-56.

Abstract

We evaluated the DMFT (decayed, missing and filled teeth) index and the prevalence of candidiasis, linear gingival erythema, oral hairy leukoplakia, herpes simplex, aphthous ulcers, Kaposi's sarcoma and lymphoma, as well as the association with TCD4 count, viral load (VL) and antiretroviral therapy (ART) in 140 HIV-infected adult individuals. A standardized examination to determine the DMFT index and the presence of oral lesions was conducted. Demographic data, TCD4 count and use of ART were obtained from medical records. A high number of decayed teeth detected among patients undergoing ART resulted in a mean DMFT of 16.9 teeth. It was observed that 24.2% of the individuals had at least one oral lesion. Candidiasis was the most frequent lesion and was associated with the TCD4 count. Oral hairy leukoplakia was associated with an increased VL. Regular use of ART was inversely associated with the occurrence of lesions. Overall, the studied population showed low prevalence of oral lesions and high DMFT index. The use of ART seems to reduce the occurrence of these lesions. Higher TCD4 count and a lower VL were associated with an improved oral health status in HIV + individuals.

摘要

我们评估了 DMFT(龋齿、缺失和填补的牙齿)指数以及念珠菌病、线性牙龈红斑、口腔毛状白斑、单纯疱疹、口腔溃疡、卡波西肉瘤和淋巴瘤的患病率,以及与 TCD4 计数、病毒载量 (VL) 和抗逆转录病毒治疗 (ART) 的关联,共纳入 140 名 HIV 感染的成年个体。对这些个体进行了标准化的口腔检查,以确定 DMFT 指数和口腔病变的存在。从病历中获取了人口统计学数据、TCD4 计数和使用 ART 的情况。正在接受 ART 治疗的患者中发现大量龋齿,导致平均 DMFT 为 16.9 颗牙齿。观察到 24.2%的个体至少有一种口腔病变。念珠菌病是最常见的病变,与 TCD4 计数相关。口腔毛状白斑与 VL 增加相关。定期使用 ART 与病变的发生呈负相关。总体而言,研究人群的口腔病变发生率较低,DMFT 指数较高。ART 的使用似乎降低了这些病变的发生。较高的 TCD4 计数和较低的 VL 与 HIV+个体的口腔健康状况改善相关。

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