Geboes K, De Wolf-Peeters C, Rutgeerts P, Vantrappen G, Desmet V
Dis Colon Rectum. 1978 Sep;21(6):420-5. doi: 10.1007/BF02586719.
Submucosal tumors of the colon are rare and require alertness on the part of the physician for early diagnosis. These tumors may not cause symptoms before attaining large size. In most cases the clinical histories are atypical. Because of the possibility of malignancy, adequate diagnosis and treatment are necessary. This report deals with 25 cases of submucosal tumors of the colon. The tumor series included seven leiomyomas, one granular-cell myoblastoma, two leiomyosarcomas, seven carcinoid tumors, six lipomas, one lymphangioma, and one neurofibroma. Five of the tumors were asymptomatic. The endoscopic appearances of the tumors, although not diagnostic, may give some indications as to their natures. Endoscopic removal is possible, although it is indicated for high-risk patients only. Because submucosal tumors may be malignant, and because differentiation from secondary tumors (metastases) or tumor-like lesions is difficult without histologic examination, complete removal of the tumor is the treatment of choice.
结肠黏膜下肿瘤较为罕见，需要医生保持警惕以便早期诊断。这些肿瘤在长得很大之前可能不会引起症状。在大多数情况下，临床病史并不典型。由于存在恶变的可能性，进行充分的诊断和治疗很有必要。本报告涉及25例结肠黏膜下肿瘤。肿瘤系列包括7例平滑肌瘤、1例颗粒细胞瘤、2例平滑肌肉瘤、7例类癌肿瘤、6例脂肪瘤、1例淋巴管瘤和1例神经纤维瘤。其中5例肿瘤无症状。肿瘤的内镜表现虽然不能确诊，但可能会对其性质提供一些线索。内镜切除是可行的，不过仅适用于高危患者。由于黏膜下肿瘤可能是恶性的，而且在没有组织学检查的情况下很难与继发性肿瘤（转移瘤）或肿瘤样病变相鉴别，所以完整切除肿瘤是首选的治疗方法。
