Ninet J, Vigneron M, Cochet P, Neidecker J, d'Agrosa M C, Bastien O, de Riberolles C, Champsaur G
Service de chirurgie thoracique et cardiaque C, BP Lyon-Montchat.
Arch Mal Coeur Vaiss. 1990 Sep;83(10):1571-7.
Eleven patients aged 7 to 58 years were placed on assisted circulation with Pierce (2 cases) or Abiomed (9 cases) external prosthetic ventricles as a bridge to cardiac transplantation. The indications were terminal cardiac failure following cardiomyopathy (7 cases), decompensated ischemic heart disease (3 cases) and subacute post-transplantation rejection (1 case). The duration of the assisted circulation ranged from 24 hours to 11 days. All patients were transplanted but 3 died after transplantation (27%). The circulatory assistance was satisfactory in all patients as shown by the regression of clinical signs of low cardiac output and the normalisation of diuresis. The complications observed during assisted circulation and after cardiac transplantation were: haemorrhage (36%), infection (27%) and thromboembolism (9%). These preliminary results with a 72% post-transplantation survival rate, show that both systems are effective "bridges to cardiac transplantation". The Abiomen device is excellent value for money and relatively simple to install and represents a good compromise between the sophisticated techniques of circulatory assistance and the problems of the cost of health care.
11名年龄在7岁至58岁之间的患者使用皮尔斯（2例）或阿比奥梅德（9例）体外人工心室进行辅助循环，作为心脏移植的桥梁。适应症为心肌病后终末期心力衰竭（7例）、失代偿性缺血性心脏病（3例）和亚急性移植后排斥反应（1例）。辅助循环的持续时间为24小时至11天。所有患者均接受了移植，但3例在移植后死亡（27%）。正如心输出量降低的临床体征消退和尿量恢复正常所示，所有患者的循环辅助效果均令人满意。在辅助循环期间和心脏移植后观察到的并发症有：出血（36%）、感染（27%）和血栓栓塞（9%）。这些初步结果显示移植后存活率为72%，表明这两种系统都是有效的“心脏移植桥梁”。阿比奥梅德装置性价比高，安装相对简单，在复杂的循环辅助技术和医疗保健成本问题之间达成了良好的平衡。
