Kuske S, Lessing C, Lux R, Schmitz A, Schrappe M
Institut für Patientensicherheit der Rheinischen Friedrich-Wilhelms-Universität Bonn, Bonn.
Gesundheitswesen. 2012 Feb;74(2):79-86. doi: 10.1055/s-0030-1269838. Epub 2011 Jan 12.
The aim of this project was to identify international patient safety indicators used for medication safety (AMTS-PSI), to evaluate the validity by a panel of experts, and to examine the transfer of the international AMTS-PSI to the pharmacotherapy care of the German Health Care System. It was part of the "Agenda for the Improvement of Medication Safety 2008/2009 in Germany" of the German Ministry of Health.
National and international AMTS-PSI were identified by a systematic review (Set 1). To define patient safety indicators as a subdivision of quality indicators, the indicators were categorised by patient's risk of adverse drug events and the degree of prevention (Set 2). Duplicates of AMTS-PSI were excluded (Set 3). The content validity was determined by the "qualify-instrument" on categories "relevance", "evidence" and "feasibility". This process was based on a double-stage Delphi method. The transferability to the pharmacotherapy care of the German Health Care System of the AMTS-PSI was evaluated (Set 4).
385 AMTS-indicators were identified. The categorisation resulted in a set of 40 AMTS-PSI, 20 AMTS-PSI were excluded. The evaluation of the validity by the "qualify-instrument" and the transferability resulted in a set of 14 for the stationary, ambulant sector. They also were valid for both sectors.
An AMTS-PSI-set was identified by a systematic review and recognised as valid for transferring it to the pharmacotherapy care of the German Health Care System by the "qualify-instrument". These 14 AMTS-PSI are mainly characterised by their relevance. Before using these indicators in practice, their further operationalisation seems necessary.
本项目旨在确定用于药物安全的国际患者安全指标（AMTS - PSI），由专家小组评估其有效性，并研究国际AMTS - PSI在德国医疗保健系统药物治疗护理中的适用性。它是德国卫生部“2008/2009年德国药物安全改进议程”的一部分。
通过系统综述确定国家和国际AMTS - PSI（第1组）。为将患者安全指标定义为质量指标的一个细分，根据患者药物不良事件风险和预防程度对指标进行分类（第2组）。排除AMTS - PSI的重复项（第3组）。通过“质量工具”在“相关性”、“证据”和“可行性”类别上确定内容有效性。此过程基于两阶段德尔菲法。评估AMTS - PSI在德国医疗保健系统药物治疗护理中的可转移性（第4组）。
确定了385个AMTS指标。分类后得到一组40个AMTS - PSI，排除了20个AMTS - PSI。通过“质量工具”对有效性和可转移性的评估得出一组适用于住院和门诊部门的14个指标。它们对两个部门均有效。
通过系统综述确定了一组AMTS - PSI，并被“质量工具”认可为可转移至德国医疗保健系统药物治疗护理中。这14个AMTS - PSI主要以其相关性为特征。在实际使用这些指标之前，似乎有必要进一步实施它们。
