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儿童和青少年的黄瘤病与遗传性高脂蛋白血症

Xanthomas and the inherited hyperlipoproteinemias in children and adolescents.

作者信息

Maher-Wiese V L, Marmer E L, Grant-Kels J M

机构信息

Department of Dermatology, Brown University, Roger Williams Hospital, Providence, Rhode Island.

出版信息

Pediatr Dermatol. 1990 Sep;7(3):166-73. doi: 10.1111/j.1525-1470.1990.tb00275.x.

DOI:10.1111/j.1525-1470.1990.tb00275.x
PMID:2123340
Abstract

Early recognition of the hyperlipoproteinemias is a crucial element in preventing premature coronary artery disease. Xanthomas provide a cutaneous marker of the silent, underlying pathology. Identifying them, and understanding their relation to the inherited hyperlipoproteinemias may facilitate early diagnosis of hyperlipoproteinemias in pediatric patients. The dermatologist plays an important role in identifying these lesions and in subsequently facilitating prompt referral and treatment.

摘要

早期识别高脂蛋白血症是预防早发性冠状动脉疾病的关键因素。黄瘤是潜在隐匿病理状态的皮肤标志物。识别黄瘤并了解它们与遗传性高脂蛋白血症的关系,可能有助于早期诊断儿科患者的高脂蛋白血症。皮肤科医生在识别这些损害以及随后促进及时转诊和治疗方面发挥着重要作用。

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Xanthomas and the inherited hyperlipoproteinemias in children and adolescents.儿童和青少年的黄瘤病与遗传性高脂蛋白血症
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引用本文的文献

1
Multiple large xanthomas: A case report.多发性大睑黄瘤:一例报告。
Oncol Lett. 2016 Dec;12(6):4327-4332. doi: 10.3892/ol.2016.5282. Epub 2016 Oct 18.
2
Squamous cell carcinoma developing in a long-standing case of tuberous xanthoma: An incident unreported hitherto.在一例长期存在的结节性黄瘤病例中发生的鳞状细胞癌:迄今未报告的病例。
Indian Dermatol Online J. 2015 Dec;6(Suppl 1):S5-8. doi: 10.4103/2229-5178.171053.
3
The outer frontier: the importance of lipid metabolism in the skin.前沿领域:脂质代谢在皮肤中的重要性。
J Lipid Res. 2009 Apr;50 Suppl(Suppl):S417-22. doi: 10.1194/jlr.R800039-JLR200. Epub 2008 Oct 31.