Rezaie Roozbeh, Simos Panagiotis G, Papanicolaou Andrew C, Castillo Eduardo M, Moser Dana C, Passaro Antony D, Fletcher Jack M
Department of Pediatrics, Children's Learning Institute, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
Neuroreport. 2011 Feb 16;22(3):136-40. doi: 10.1097/WNR.0b013e3283435c37.
The neural origins of the cortical response to rare sensory events remain poorly understood. Using simultaneous event-related potentials and magnetic resonance imaging, we investigated the anatomical profile of regional activity at various processing stages during performance of auditory and visual variants of an oddball paradigm. The earliest rarity-detection response was found in sensory-specific cortices, rapidly spreading to tertiary association areas, mesial temporal and frontal cortices by 150-200 ms. P3m-related activity was not found in sensory-specific cortices. On the basis of the anatomic distribution of P3m-related activity, this component is likely to reflect more generalized cognitive abilities hosted by association cortical regions.
大脑皮层对罕见感觉事件的反应的神经起源仍知之甚少。我们利用同步事件相关电位和磁共振成像，研究了在执行听觉和视觉oddball范式变体时，不同处理阶段区域活动的解剖学特征。最早的稀有性检测反应出现在感觉特异性皮层，到150 - 200毫秒时迅速扩散到三级联合区、颞叶内侧和额叶皮层。在感觉特异性皮层中未发现与P3m相关的活动。基于与P3m相关活动的解剖分布，这一成分可能反映了联合皮层区域所具备的更广泛的认知能力。
