Department of Anatomy, Cell Biology, Physiology and Biophysics, Institute of Biology, State University of Campinas (UNICAMP), Campinas, São Paulo 13083-970, Brazil.
Anat Rec (Hoboken). 2011 Feb;294(2):283-6. doi: 10.1002/ar.21297. Epub 2010 Dec 2.
In mdx mice, intrinsic laryngeal muscles are spared and sternomastoid muscles are affected, showing cycles of muscle regeneration. We observed that utrophin and acetylcholine receptors are fragmented only in affected muscles, providing further evidence that changes in the overall distribution of molecules at dystrophic neuromuscular junctions may be correlated with muscle regeneration.
在 mdx 小鼠中，内在喉肌未受影响，而胸锁乳突肌受到影响，表现出肌肉再生的周期。我们观察到，只有在受影响的肌肉中，utrophin 和乙酰胆碱受体才会发生碎片化，这进一步证明了在营养不良的神经肌肉接头处，分子的总体分布变化可能与肌肉再生有关。
