[Screening of alpha-amino acid ester hydrolase producing strain and synthesis of cephalexin by Pseudomonas aeruginosa].
作者信息
Wang M, Wang Z, Yue H, Han W, Jiao Q
机构信息
Institute of Microbiology, Academia Sinica, Beijiag.
出版信息
Wei Sheng Wu Xue Bao. 1990 Jun;30(3):238-41.
PMID:2123585
Abstract
From ten genera and 146 bacterial strains, 22 strains producing alpha-amino acid ester hydrolase were selected. Among them, AS 1.586 and 41-2 were the best. The optimal conditions for synthesis of cephalexin by pseudomonas aeruginosa 1.204 were investigated. The optimal pH and temperature for enzymatic synthesis reaction was pH 6.8 and 25 degrees C, respectively. By using 1% 7-ADCA, 3% PGME and 4% biomass, about 70% of 7-ADCA was converted to cephalexin under the mentioned conditions.
摘要
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