Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, The University of Texas Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA.
Am J Obstet Gynecol. 2011 Mar;204(3):263.e1-4. doi: 10.1016/j.ajog.2010.12.004. Epub 2011 Jan 14.
The purpose of this study was to report the frequency of fetal growth restriction (FGR) based on indication for late preterm birth (LPTB).
Singleton live born pregnancies that were delivered from 34-36 weeks 6 days of gestation over a 1-year period at a tertiary care medical center were studied. Indications for delivery were categorized as spontaneous (spontaneous preterm birth or premature rupture of membranes), medically indicated, or elective. A customized birthweight percentile was calculated for each pregnancy; the rate of FGR was compared based on indication for LPTB.
There were 482 LPTBs that met all criteria. Customized birthweight percentiles (median; interquartile range) were different among groups (spontaneous, 45.5%; 20.8-73.5%; medically indicated, 26.9%; 4.1-63.6%; elective, 45.9%; 22.2-78.3%; P = .001). The rate of FGR was also different among groups (spontaneous, 13%; medically indicated, 32%; elective, 21%; P = .001).
With the use of customized birthweight standards, we found that FGR complicated approximately one-third of all cases of medically indicated LPTB.
本研究旨在报告基于晚期早产（LPTB）指征的胎儿生长受限（FGR）的频率。
对一家三级保健医疗中心在 1 年期间于 34-36 周 6 天分娩的单胎活产妊娠进行研究。分娩指征分为自发性（自发性早产或胎膜早破）、医学指征和选择性。为每个妊娠计算了定制的体重百分位数；根据 LPTB 的指征比较了 FGR 的发生率。
共有 482 例符合所有标准的 LPTB。组间的定制体重百分位数（中位数；四分位距）不同（自发性组，45.5%；20.8-73.5%；医学指征组，26.9%；4.1-63.6%；选择性组，45.9%；22.2-78.3%；P =.001）。FGR 的发生率也不同（自发性组 13%；医学指征组 32%；选择性组 21%；P =.001）。
使用定制的体重标准，我们发现大约三分之一的医学指征性 LPTB 伴有 FGR。
