胸腺瘤相关重症肌无力，无乙酰胆碱受体抗体。

Thymoma-associated myasthenia gravis without acetylcholine receptor antibodies.

机构信息

Neurological Department, A. Manzoni Hospital, Via Dell'Eremo 9/11, 23900 Lecco, Italy.

出版信息

J Neurol Sci. 2011 Mar 15;302(1-2):112-3. doi: 10.1016/j.jns.2010.12.013. Epub 2011 Jan 13.

DOI:10.1016/j.jns.2010.12.013

Abstract

Patients with myasthenia gravis and thymoma usually present antibodies to the acetylcholine receptor (AchR-Ab). Only two cases of thymoma-associated myasthenia gravis without AchR-Ab have been previously reported. We describe a case of seronegative thymoma-associated myasthenia gravis as a further evidence of the variability of myasthenia gravis in terms of antibody profile and thymic pathological findings.

摘要

患有重症肌无力和胸腺瘤的患者通常会出现乙酰胆碱受体 (AchR-Ab) 抗体。以前仅报道过两例无 AchR-Ab 的胸腺瘤相关重症肌无力病例。我们描述了一例血清阴性胸腺瘤相关重症肌无力病例，进一步证明了重症肌无力在抗体谱和胸腺病理发现方面的变异性。