Pirke K M, Schweiger U, Broocks A, Tuschl R J, Laessle R G
Max-Planck-Institut für Psychiatrie, Division of Psychoneuroendocrinology, München, FR Germany.
Clin Endocrinol (Oxf). 1990 Sep;33(3):345-53. doi: 10.1111/j.1365-2265.1990.tb00499.x.
Thirty-one young female athletes and 13 age-matched sedentary controls were studied throughout one menstrual cycle or over a 6 week period. Blood was sampled on 5 days per week. Episodic gonadotrophin secretion was measured in the early follicular phase and in the late luteal phase by blood sampling over a 12-h period at 15-min intervals. Eight athletes had anovulatory cycles, nine had impaired progesterone (P4) secretion during the luteal phase and 14 had normal cycles as judged from oestradiol (E2) and P4 plasma levels. Athletes with normal cycles had shorter cycles, lower E2 maxima at midcycle, and lower E2 and P4 concentrations during the luteal phase than had sedentary controls. Episodic luteinizing hormone (LH) secretion in the early follicular phase was significantly impaired in the anovulatory athletes: the average LH values over 12 h and the number of secretion episodes were significantly reduced. No significant changes were seen in follicle stimulating hormone secretion.
对31名年轻女运动员和13名年龄匹配的久坐不动的对照者进行了为期一个月经周期或6周的研究。每周5天采集血样。在卵泡早期和黄体晚期，通过每隔15分钟采集一次血样，持续12小时，来测量促性腺激素的间歇性分泌。根据雌二醇（E2）和孕酮（P4）血浆水平判断，8名运动员有无排卵周期，9名在黄体期孕酮（P4）分泌受损，14名周期正常。与久坐不动的对照者相比，周期正常的运动员周期更短，周期中期E2峰值更低，黄体期E2和P4浓度更低。无排卵运动员在卵泡早期促黄体生成素（LH）的间歇性分泌明显受损：12小时内的平均LH值和分泌次数显著减少。卵泡刺激素分泌未见明显变化。
