Pharmacol Res. 2011 May;63(5):362-5. doi: 10.1016/j.phrs.2011.01.006. Epub 2011 Jan 15.
Excipients are largely used by pharmaceutical industry to guarantee preservation and stability and confer shape, volume and consistency to pharmaceutical preparations. They are particularly important in medicines intended for prescription in children since they often play a critical role in manufacturing of suitable paediatric formulations. It was generally believed that excipients were inert substances; on the contrary, it is actually well known that excipients are far from being inactive and much more interest is growing about safety issues associated with their extensive use by pharmaceutical industry in general, and for manufacturing of paediatric drugs in particular.
辅料在很大程度上被制药行业用于保证药物的保存和稳定性，并赋予药物制剂形状、体积和一致性。它们在儿童处方药物中尤为重要，因为它们在制造合适的儿科制剂中常常起着关键作用。人们普遍认为辅料是惰性物质；相反，实际上人们已经充分认识到辅料远非惰性，并且人们越来越关注与制药行业广泛使用辅料相关的安全性问题，特别是在制造儿科药物方面。
