Department of Zoology, University of British Columbia, Vancouver BC, Canada.
Cell. 2011 Jan 21;144(2):170-1. doi: 10.1016/j.cell.2011.01.006.
Polycomb group (PcG) proteins mediate long-range associations between Hox genes, which correlate with gene repression in vivo. Bantignies et al. (2011) identify a physiological role for the nuclear localization of Hox genes in PcG-mediated gene silencing, strengthening the evidence that nuclear positioning regulates gene expression.
多梳蛋白（PcG）家族蛋白介导 Hox 基因之间的长距离关联，这与体内基因抑制相关。Bantignies 等人（2011 年）发现 Hox 基因在 PcG 介导的基因沉默中的核定位的生理作用，这进一步证实了核定位调节基因表达的证据。
