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预测小儿腺样体扁桃体切除术后不良呼吸事件的多导睡眠图变量。

Polysomnographic variables predictive of adverse respiratory events after pediatric adenotonsillectomy.

作者信息

Jaryszak Eric M, Shah Rahul K, Vanison Christopher C, Lander Lina, Choi Sukgi S

机构信息

Children's National Medical Center, George Washington University School of Medicine, Washington, DC, USA.

出版信息

Arch Otolaryngol Head Neck Surg. 2011 Jan;137(1):15-8. doi: 10.1001/archoto.2010.226.

DOI:10.1001/archoto.2010.226
PMID:21242540
Abstract

OBJECTIVE

To determine polysomnographic (PSG) variables that may potentially predict adverse respiratory events after pediatric adenotonsillectomy.

DESIGN

Retrospective, case-control study.

SETTING

Free-standing academic tertiary-care pediatric hospital.

PATIENTS

The study included 1131 patients undergoing adenotonsillectomy by 2 attending surgeons. There were no exclusion criteria.

MAIN OUTCOME MEASURES

Variables from preoperative PSGs were analyzed to determine predictors of postoperative respiratory complications. Logistic regression analysis was performed.

RESULTS

A total of 151 patients (13.4%) underwent preoperative PSG. Twenty-three of these patients (15.2%) had adverse respiratory events. The primary adverse event was desaturation requiring supplemental oxygen therapy, with 1 case of postobstructive pulmonary edema. Patients with adverse events had a significantly higher apnea-hypopnea index) (31.8 vs 14.1; P = .001), higher hypopnea index (22.6 vs 8.9; P = .004), higher body mass index (z score, 1.43 vs 0.70; P = .02), and lower nadir oxygen saturation (72% vs 84%; P <.001). Patients with adverse events had a prolonged hospital course (odds ratio, 32.1; 95% confidence interval, 7.8-131.4). There were no differences in age or other PSG variables. There were no intubations or mortalities.

CONCLUSIONS

Polysomnography may be used to predict which patients are at higher risk for adverse respiratory events after adenotonsillectomy. Such knowledge is valuable for planning optimal postoperative management and intraoperative anesthesia. Predictors of increased respiratory complications include apnea-hypopnea index, hypopnea index, body mass index, and nadir oxygen saturation.

摘要

目的

确定可能预测小儿腺样体扁桃体切除术后不良呼吸事件的多导睡眠图(PSG)变量。

设计

回顾性病例对照研究。

地点

独立的学术性三级儿科医院。

患者

该研究纳入了由2名主治外科医生实施腺样体扁桃体切除术的1131例患者。无排除标准。

主要观察指标

分析术前PSG的变量以确定术后呼吸并发症的预测因素。进行逻辑回归分析。

结果

共有151例患者(13.4%)进行了术前PSG检查。其中23例患者(15.2%)发生了不良呼吸事件。主要不良事件是需要补充氧气治疗的血氧饱和度下降,伴有1例阻塞性肺水肿。发生不良事件的患者呼吸暂停低通气指数显著更高(31.8对14.1;P = .001),低通气指数更高(22.6对8.9;P = .004),体重指数更高(z评分,1.43对0.70;P = .02),最低血氧饱和度更低(72%对84%;P <.001)。发生不良事件的患者住院时间延长(比值比,32.1;95%置信区间,7.8 - 131.4)。年龄或其他PSG变量无差异。无插管或死亡病例。

结论

多导睡眠图可用于预测哪些患者在腺样体扁桃体切除术后发生不良呼吸事件的风险更高。这些信息对于规划最佳术后管理和术中麻醉很有价值。呼吸并发症增加的预测因素包括呼吸暂停低通气指数、低通气指数、体重指数和最低血氧饱和度。

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