Robison Jacob G, Otteson Todd D
Department of Otolaryngology, University of Pittsburgh Medical Center, PA 15224, USA.
Arch Otolaryngol Head Neck Surg. 2011 Jan;137(1):74-7. doi: 10.1001/archoto.2010.225.
To determine the prevalence of hoarseness in the cleft palate population.
Retrospective chart review from a tertiary pediatric hospital's craniofacial clinic.
Nonsyndromic patients with cleft palate who had undergone cleft palate repair were eligible for inclusion. Patients were excluded if they had previously undergone a tracheostomy or if they had significant hearing loss. A total of 487 patients met the inclusion criteria.
Medical records were reviewed for demographic data, presence of hoarseness, velopharyngeal insufficiency, symptoms of gastroesophageal reflux disease, and laryngoscopic findings.
Of the 487 patients, 27 (5.5%) had complaints of hoarseness: 13 boys and 14 girls. The average age at initial complaint was 4.6 years, with slight differences according to sex: 4.2 years for boys and 5.0 years for girls. Of those with hoarseness, 19 (70%) had velopharyngeal insufficiency, and 8 (30%) had concomitant symptoms of possible gastroesophageal reflux disease. Eleven patients underwent either direct or flexible laryngoscopy: 9 (33%) had vocal fold nodules, and 2 (7%) had edema and/or mucosal thickening of the vocal folds.
The 5.5% prevalence of hoarseness in this study is similar to the reported prevalence of 6% to 34% in the normal pediatric population. These results suggest that there is no difference in the cleft palate population and that hoarseness is either underrecognized and/or underreported. More studies are needed to fully elucidate the true prevalence of hoarseness in the cleft palate population and any correlation of hoarseness with velopharyngeal insufficiency and/or gastroesophageal reflux disease.
确定腭裂人群中声音嘶哑的患病率。
对一家三级儿科医院颅面诊所的病历进行回顾性研究。
接受过腭裂修复术的非综合征性腭裂患者符合纳入标准。曾行气管切开术或有严重听力损失的患者被排除。共有487例患者符合纳入标准。
查阅病历以获取人口统计学数据、声音嘶哑情况、腭咽闭合不全情况、胃食管反流病症状及喉镜检查结果。
487例患者中,27例(5.5%)有声音嘶哑主诉:13例男孩,14例女孩。首次出现症状的平均年龄为4.6岁,性别间略有差异:男孩为4.2岁,女孩为5.0岁。在声音嘶哑的患者中,19例(70%)有腭咽闭合不全,8例(30%)伴有可能的胃食管反流病症状。11例患者接受了直接喉镜或纤维喉镜检查:9例(33%)有声带小结,2例(7%)有声带水肿和/或黏膜增厚。
本研究中声音嘶哑的患病率为5.5%,与正常儿科人群报道的6%至34%的患病率相似。这些结果表明腭裂人群中无差异,且声音嘶哑要么未被充分认识,要么未被充分报道。需要更多研究来全面阐明腭裂人群中声音嘶哑的真实患病率以及声音嘶哑与腭咽闭合不全和/或胃食管反流病的任何相关性。