Deengam Nalinee, Prathanee Benjamas, Laohakittikul Chanticha
Department of Otorhinolaryngology, Faculty of Medicine Khon Kaen University Khon Kaen Thailand.
Mekong Health Science Research Institute, Khon Kaen University Khon Kaen Thailand.
Laryngoscope Investig Otolaryngol. 2025 May 22;10(3):e70165. doi: 10.1002/lio2.70165. eCollection 2025 Jun.
To determine the prevalence of voice disorders, relationships between voice disorders and hypernasality, patterns of compensatory articulation disorders (CAD), acoustic characteristics, and associated factors in children with cleft palate with/without (CP ± L).
The study consisted of 60 children with CP ± L, aged 7-12 years, who had undergone palate repair with/without cleft lip repair. Data were collected by evaluating voice quality using the GIRBAS scale (grade, instability, roughness, breathiness, asthenia, and strain). The Computerized Speech Lab (CSL) was used to evaluate the acoustic characteristics, including fundamental frequency ( ), shimmer, jitter, and maximum phonation time (MPT). A Fiber Optic Laryngoscope (FOL) was utilized to conduct laryngeal investigations. Spearman's Rank Correlation statistics were used to investigate correlations.
Prevalence of voice disorders in children with CP ± L was 30% (18/60 cases). Laryngeal examinations showed that 33.33% had exhibited vocal nodules, and 13.34% had vocal cord edema. Regarding assessments of acoustic characteristics, children with voice disorders displayed significantly higher jitter and shimmer values than those with normal voices ( < 0.05). (mean differences for jitter and shimmer /a:/ being -0.99 and -3.60), there were positive statistically significant relationships between voice disorders and severity of hypernasality at both the word and sentence levels ( = 0.46, = 0.55); between voice disorders and the number of CAD patterns at both the word and sentence levels, ( = 0.30, = 0.40).
The prevalence of voice disorders in children with CP ± L was 30%. The severity of voice disorders from the GIRBAS scores was significantly correlated to the severity of hypernasality and the number of CAD patterns.
A cross-sectional study.
确定伴有或不伴有唇裂（CP±L）的腭裂患儿嗓音障碍的患病率、嗓音障碍与鼻音过重之间的关系、代偿性构音障碍（CAD）的模式、声学特征及相关因素。
本研究纳入60例年龄在7至12岁之间、接受过腭裂修复术（伴有或不伴有唇裂修复术）的CP±L患儿。通过使用GIRBAS量表（分级、不稳定性、粗糙度、气息声、无力感和紧张度）评估嗓音质量来收集数据。使用计算机语音实验室（CSL）评估声学特征，包括基频、微扰、抖动和最长发声时间（MPT）。使用光纤喉镜（FOL）进行喉部检查。采用Spearman等级相关统计分析相关性。
CP±L患儿嗓音障碍的患病率为30%（18/60例）。喉部检查显示，33.33%的患儿有声带小结，13.34%的患儿有声带水肿。在声学特征评估方面，嗓音障碍患儿的抖动和微扰值显著高于嗓音正常的患儿（P<0.05）。（/a:/音的抖动和微扰平均差异分别为-0.99和-3.60），在单词和句子层面，嗓音障碍与鼻音过重的严重程度之间均存在统计学上的显著正相关（r=0.46，r=0.55）；在单词和句子层面，嗓音障碍与CAD模式的数量之间也存在相关性（r=0.30，r=0.40）。
CP±L患儿嗓音障碍的患病率为30%。GIRBAS评分中嗓音障碍的严重程度与鼻音过重的严重程度及CAD模式的数量显著相关。
横断面研究。
2级。
