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[1990 - 2009年间罗马尼亚及雅西县儿童乙型和丙型病毒性肝炎的流行病学演变趋势]

[Trends in epidemiological evolution of viral hepatitis B and C , in children , Romania and Iaşi county between 1990-2009].

作者信息

Azoicăi Alice Nicoleta, Moraru Evelina, Duca Elena, Azoicăi Doina

机构信息

Clinica a II-a Pediatrie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 2010 Jul-Sep;114(3):731-7.

Abstract

UNLABELLED

Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are the frequent causes of acute and chronic hepatitis worldwide and the leading causes for hepatic cirrhosis and liver cancer. There is a distinct geographical variation in VHB and VHC incidence in adult and child.

AIM

To assess the evolution trend of VHB and VHC incidence in child, in Romania and Iasi County, during the last two decades.

MATERIAL AND METHODS

Data were obtained using information from the Reporting National System for acute viral hepatitis A, B, and C, from various geographical areas of Romania. Some systematical errors of information were identified, without significant influence of results and conclusions.

RESULTS

Results highlighted an incidence peak of VHB in Romania, in 1989, and in Iaşi county, in 1991 (43.1, respectively 41.2 per thousand inhabitants). The VHB incidence trend decreased after the implementation of vaccination programme, especially in children < 4 years old.

CONCLUSIONS

The study remarked the necessity of viral hepatitis surveillance programme continuity in Romania and the importance of prevention measures including, for VHB, an optimal vaccination.

摘要

未标注

乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)感染是全球急性和慢性肝炎的常见病因,也是肝硬化和肝癌的主要病因。成人和儿童中HBV和HCV的发病率存在明显的地域差异。

目的

评估罗马尼亚和雅西县过去二十年儿童中HBV和HCV发病率的演变趋势。

材料与方法

数据来自罗马尼亚不同地理区域的国家急性甲型、乙型和丙型病毒性肝炎报告系统。发现了一些信息的系统性错误,但对结果和结论没有显著影响。

结果

结果显示,罗马尼亚在1989年、雅西县在1991年出现了HBV发病率峰值(分别为每千名居民43.1例和41.2例)。实施疫苗接种计划后,HBV发病率呈下降趋势,尤其是在4岁以下儿童中。

结论

该研究指出罗马尼亚病毒性肝炎监测计划持续开展的必要性,以及预防措施的重要性,包括对HBV进行最佳疫苗接种。

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