Chiosac Alina Andreea Andreescu, Manole Alina, Gorduza E V, Stamatin Maria, Titianus Monica, Ivan A
Doctorand al Universităţii de Medicină şi Farmacie Gr.T. Popa Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2010 Jul-Sep;114(3):836-40.
Congenital abnormalities (CA) are deviations from the normal embryonic development that appear antenatal and they are characterized by the alteration of the morphology and function of an organ, system of organs or even of the entire body.
The study, on a period of eight years, included 1685 children with CA, from which 58% were males and 50% were from the country-side.
It has been observed that 36% of the CA cases were premature births and 64% were normal term births. Also, 21% of the children with CA weighed less than 2700 grams at birth and 79% weighed more than 2700 grams at birth. The birth's APGAR score has been less than 7 in 30% of the cases and higher than 7 in 70% of the cases. 72% of the cases were natural births and 28% were caesarian births. 88% of the CA cases were singular congenital abnormalities and 12% were multiple congenital abnormalities. 24% of the CA were cardiac abnormalities and 21% were skeletal abnormalities. 3% of the subjects of the study have died, of which 69% died from cardiac abnormalities, 22% from hydrocephalus abnormalities, 7% from diaphragmatic hernia and 2% from renal congenital abnormalities.
先天性异常（CA）是指产前出现的与正常胚胎发育的偏差，其特征是器官、器官系统甚至整个身体的形态和功能发生改变。
这项为期八年的研究纳入了1685例先天性异常患儿，其中58%为男性，50%来自农村。
观察到36%的先天性异常病例为早产，64%为足月产。此外，21%的先天性异常患儿出生时体重低于2700克，79%出生时体重超过2700克。30%的病例出生时阿氏评分低于7分，70%的病例高于7分。72%的病例为自然分娩，28%为剖宫产。88%的先天性异常病例为单发先天性异常，12%为多发先天性异常。24%的先天性异常为心脏异常，21%为骨骼异常。该研究中有3%的受试者死亡，其中69%死于心脏异常，22%死于脑积水异常，7%死于膈疝，2%死于先天性肾脏异常。
