Titianu Monica, Schaas Carmina, Stamatin Maria, Costăchescu G, Onofriescu M
Universitatea de Medicină şi Farmacie "Gr. T. Popa" Iaşi, Facultatea de Medicină.
Rev Med Chir Soc Med Nat Iasi. 2011 Jul-Sep;115(3):845-50.
To update the data on the incidence of congenital malformations in our area and emphasize the importance of prenatal diagnosis.
The study was conducted over a period of ten years and included 2211 cases with congenital malformations. Such parameters as the incidence of malformations over these years, gestational age at the moment of diagnosis, and mortality from congenital malformations were followed. Statistical and graphical data were processed with the help of SPSS 16.0 and MS Excel software.
The total prevalence of malformations was 3.52%, comparable with the data in the literature. Over this period a number of 262 cases (11.8%) ended in spontaneous miscarriage or termination of pregnancy for fetal abnormalities. A significant percentage of these pregnant women gave birth to their child, many of them dying shortafter.
Congenital malformations remain the leading cause of mortality in neonates. In Romania, the advanced techniques of prenatal diagnosis being used only in specialized centers, and a large number of cases may escape early diagnosis. This study underlines the importance of a correct assessment of fetuses so that the discovery of fetal abnormalities at birth not to be a surprise.
