Natural Product Chemistry Division, Indian Institute of Integrative Medicine (CSIR), Canal Road, Jammu, India 180001.
Org Lett. 2011 Feb 18;13(4):576-9. doi: 10.1021/ol102723c. Epub 2011 Jan 18.
The use of manganese(III) acetate allows the direct synthesis of diverse arrays of [4.3.0] bicyclic carbohydrate-based γ-lactone building blocks from glycals. A mechanism to explain the high regio- and stereoselectivity is proposed. The new reaction has the potential to generate libraries for biological screening.
醋酸锰(III)允许直接从糖醛合成各种[4.3.0]双环碳水化合物基γ-内酯构建块。提出了一种解释高区域和立体选择性的机制。该新反应有可能为生物筛选生成库。
