Wolker Ryan R E, Wilson David G, Allen Andrew L, Carmalt James L
Department of Large Animal Clinical Sciences Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Vet Surg. 2011 Apr;40(3):291-8. doi: 10.1111/j.1532-950X.2010.00794.x. Epub 2011 Jan 18.
To determine whether intra-articular 70% ethyl alcohol alone (IAEA) or in combination with 2 percutaneously placed transarticular lag screws (EA-TLS) would result in arthrodesis of the equine proximal interphalangeal (PIP) joint.
Experimental.
Healthy horses (n=6), aged 1.5-3 years, free of lameness, diagonally paired front and hind PIP joints.
Six milliliters 70% ethyl alcohol was injected into randomly selected diagonally paired front and hind PIP joints. Thirty days later, 2 parallel 5.5 mm cortical screws were inserted in lag fashion across the hind PIP joints and the limbs were cast. Horses were confined for 60 days after surgery before free exercise was permitted. Serial lameness examinations were performed at 1, 6, and 10 months. Radiographs of the PIP joints were obtained before injection with alcohol (front, hind PIP joints), at 6 and 10 months (front PIP joints) and 1, 3, 6, and 10 months (hind PIP joints). At 10 months, horses were euthanatized and gross and histopathologic examination of the treated joints was performed.
Horses had variable cartilage thinning (more severe in hind PIP joints) and dorsal bone proliferation. One front and 1 hind PIP joint were fused 10 months after alcohol injection.
Ethyl alcohol injected alone or in combination with percutaneously placed transarticular lag screws failed to reliably produce fusion of the PIP joint.
确定单纯关节内注射70%乙醇(IAEA)或联合经皮置入2枚经关节拉力螺钉(EA-TLS)是否会导致马近端指间关节(PIP)融合。
实验性研究。
6匹健康马,年龄1.5 - 3岁,无跛行,对角配对的前后PIP关节。
向随机选择的对角配对的前后PIP关节内注射6毫升70%乙醇。30天后,以拉力方式在马的后PIP关节内平行插入2枚5.5毫米皮质骨螺钉,并对肢体进行石膏固定。术后将马圈养60天,之后允许自由活动。在术后1、6和10个月进行系列跛行检查。在注射乙醇前(前后PIP关节)、6和10个月(前PIP关节)以及1、3、6和10个月(后PIP关节)获取PIP关节的X线片。在10个月时,对马实施安乐死,并对治疗关节进行大体和组织病理学检查。
马出现不同程度的软骨变薄(后PIP关节更严重)和背侧骨质增生。在注射乙醇10个月后,1个前PIP关节和1个后PIP关节发生融合。
单独注射乙醇或联合经皮置入经关节拉力螺钉均未能可靠地使PIP关节融合。