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[睡眠与高血压。对7901名工人的流行病学研究]

[Sleep and hypertension. An epidemiologic study in 7,901 workers].

作者信息

Houyez F, Degoulet P, Cittee J, Fouriaud C, Jacquinet-Salord M C, Lang T, Aimé F

机构信息

Service d'informatique médicale, hôpital Broussais, Paris.

出版信息

Arch Mal Coeur Vaiss. 1990 Jul;83(8):1085-8.

PMID:2124445
Abstract

In order to evaluate possible correlations between blood pressure levels and sleep quality, 7,901 workers of both sexes living in Paris area have been the subject of a survey during their annual examination performed by workside physicians. The enquiry included questions related to sleep quantity and quality, sleeping pills consumption, awakenings, nightmares, snoring, way of life and working conditions. The information concerning these parameters was available for 7,542 people. Among them, 6,551 (86.9%) did not suffer from high blood pressure (HBP) (blood pressure less than 160/95 mmHg), 618 (8.2%) presented a high blood pressure but were not treated, 371 (4.9%) received a treatment against HBP. The average sleep duration is about 7.4 h (S.D. = 1.0) for men and about 7.6 h (S.D. = 1.0) for women (less than 0.001). It is significatively and negatively correlated with the systolic blood pressure level (SBP) (less than 0.001) and the diastolic blood pressure level (DBP) (less than 0.001). The frequency of patients complaining of nightly awakening and of snoring significatively increase with SBP (p less than 0.05) and DBP (p less than 0.001). The observed association between DBP (but not SBP) and sleep duration and nightly awakening remains significant in multivariate analysis including age, sex, tobacco smoking, alcohol and coffee consumption, use of sleeping pills and hypotensive treatment, as well as the negative correlation between SBP and nightmare frequency. The correlation between SBP or SBP and snoring was no more significant. In conclusion, a significant correlation has been found between the blood pressure levels and the sleep quality whose clinical consequences remain to be explored.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为了评估血压水平与睡眠质量之间可能存在的相关性,居住在巴黎地区的7901名男女工人在其年度体检期间接受了工作场所医生的调查。该调查包括与睡眠数量和质量、安眠药使用、觉醒、噩梦、打鼾、生活方式和工作条件相关的问题。7542人提供了有关这些参数的信息。其中,6551人(86.9%)没有高血压(血压低于160/95 mmHg),618人(8.2%)患有高血压但未接受治疗,371人(4.9%)接受了高血压治疗。男性的平均睡眠时间约为7.4小时(标准差=1.0),女性约为7.6小时(标准差=1.0)(p<0.001)。它与收缩压水平(SBP)(p<0.001)和舒张压水平(DBP)(p<0.001)呈显著负相关。抱怨夜间觉醒和打鼾的患者频率随SBP(p<0.05)和DBP(p<0.001)显著增加。在包括年龄、性别、吸烟、饮酒和咖啡消费、安眠药使用和降压治疗的多变量分析中,观察到的DBP(而非SBP)与睡眠时间和夜间觉醒之间的关联仍然显著,以及SBP与噩梦频率之间的负相关。SBP或DBP与打鼾之间的相关性不再显著。总之,已发现血压水平与睡眠质量之间存在显著相关性,其临床后果仍有待探索。(摘要截短至250字)

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