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针灸预防犬复发性中耳炎的复发:一项随机对照试验的 1 年随访。

Acupuncture prevents relapses of recurrent otitis in dogs: a 1-year follow-up of a randomised controlled trial.

机构信息

Research Unit of Complementary Therapy, Universidad Francisco de Miranda Coro, Av Río de Janeiro, Ed San Jacinto, Of. 3 Las Mercedes, Caracas, Venezuela.

出版信息

Acupunct Med. 2011 Mar;29(1):21-6. doi: 10.1136/aim.2010.002576. Epub 2011 Jan 18.

Abstract

BACKGROUND

Recurrent infections within a particular, well-localised body location are often seen in veterinary and medical practice. This condition could represent a localised or segmental immune deficiency. Recurrent canine otitis seems to be one example of this problem. It has been reported that acupuncture increased the efficacy of conventional treatment for canine otitis by >50%.

OBJECTIVE

To assess whether the relapse rate of recurrent canine otitis over 1 year can be modified by acupuncture in adult dogs.

METHODS

One-year follow-up of a randomised controlled trial. 31 dogs with a history of recurring otitis were randomised into two groups. In addition to conventional treatment, each group received four sessions of either real acupuncture, group A (n=16), or sham acupuncture, group B (n=15). The main outcome for the follow-up was the rate of acute otitis episodes in each group over 1 year, with blinded evaluation. A χ(2) test was used for statistical analysis.

RESULTS

There was one dropout in each group. Fourteen (93%) dogs in group A: were free of otitis relapses, compared with 7 (50%) in group B (p<0.01).

CONCLUSION

Acupuncture seems effective for preventing relapses in cases of recurrent canine otitis. This result suggests that acupuncture could be tested as a treatment of other recurrent localised infections. Given the ability of acupuncture to modulate neurotransmitters and opioid peptides, which can in turn modulate the immune system, the immune response to acupuncture also seems worth exploring.

摘要

背景

在兽医和医学实践中,经常会在特定的、局部化的身体部位看到反复感染。这种情况可能代表局部或节段性免疫缺陷。复发性犬耳炎似乎就是这种问题的一个例子。据报道,针灸可使犬耳炎的常规治疗效果提高>50%。

目的

评估在成年犬中,针灸是否可以改变复发性犬耳炎在 1 年内的复发率。

方法

一项随机对照试验的 1 年随访。31 只患有复发性耳炎的犬被随机分为两组。除了常规治疗外,每组还接受 4 次真针灸(A 组,n=16)或假针灸(B 组,n=15)。随访的主要结果是每组在 1 年内急性耳炎发作的次数,并进行盲法评估。使用卡方检验进行统计学分析。

结果

每组各有 1 例脱落。A 组的 14 只(93%)犬无耳炎复发,而 B 组只有 7 只(50%)(p<0.01)。

结论

针灸似乎对预防复发性犬耳炎的复发有效。这一结果表明,针灸可以作为其他复发性局部感染的治疗方法进行测试。鉴于针灸能够调节神经递质和阿片肽,进而调节免疫系统,因此对针灸的免疫反应也值得探索。

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