乌头叶蛇葡萄 I、J 和 K：来自乌头叶蛇葡萄根的新型多氧化环己烯，具有全反式相对构型。
Uvacalols I, J and K: new polyoxygenated cyclohexenes with all trans relative configurations from the roots of Uvaria calamistrata Hance.
机构信息
Guangdong Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Institute of TCM and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.
出版信息
Nat Prod Res. 2011 Jan;25(2):161-8. doi: 10.1080/14786419.2010.529810.
Three new polyoxygenated cyclohexene derivatives with all trans relative configurations, named uvacalols I, J and K (1-3), were isolated from the roots of Uvaria calamistrata Hance. Their structures were determined to be (1R, 2S, 3S, 4R)-1-ethoxyl-5-benzoyloxymethylcyclohex-5-en-2,4-diol-3-benzoate (1), 1-ethoxyl-5-benzoyloxymethylcyclohex-5-en-3,4-diol-2-benzoate (2), and 5-benzoyloxymethylcyclohex-5-en-1,2,4-triol-3-benzoate (3), respectively, by extensive NMR experiments and chemical derivatisation.
从乌药 Uvaria calamistrata Hance 的根部分离得到三个具有全反式相对构型的新的多氧化环己烯衍生物，命名为 uvacalols I、J 和 K（1-3）。它们的结构分别被确定为（1R, 2S, 3S, 4R）-1-乙氧基-5-苯甲酰氧甲基环己-5-烯-2,4-二醇-3-苯甲酸酯（1）、1-乙氧基-5-苯甲酰氧甲基环己-5-烯-3,4-二醇-2-苯甲酸酯（2）和 5-苯甲酰氧甲基环己-5-烯-1,2,4-三醇-3-苯甲酸酯（3），这是通过广泛的 NMR 实验和化学衍生化确定的。
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