Tian Yue-Feng, Li Lei-Yong, Wang Jun, Zhang Bin-Ren, Wang Ge-Hong, Xie Bo-Xiang, Yuan Ye
Department of Acupuncture and Massage, Shanxi College of TCM, Taiyuan 030024, China.
Zhongguo Zhen Jiu. 2010 Nov;30(11):933-5.
To observe the efficacy of herbal cake-separated moxibustion on the expression of erythrocyte CD58 in different ages of healthy people and explore the differences of the therapeutic effect in different ages and its mechanism.
A total of 82 health participants were divided into a young age group and a middle-old age group according to the ages. They were treated with herbal cake-separated moxibustion on Shenque (CV 8), Guanyuan (CV 4), Zusanli (ST 36), Pishu (BL 20), Shenshu (BL 23) with cake made by Shudihuang (Radiz Re hmanniae Preparata), Shanyao (Rhizoma Dioscoreae), Shanzhuyu (Fructus Corni ), etc. The treatment was given for 10 sessions once other day and each acupoint for 3 successive dosages. The mean fluorescence intensities of erythrocyte CD58 were measured by flow cytometry before and after moxibustion.
After moxibustion, erythrocyte CD58 expression were significantly higher than that before moxibustion in two groups (both P < 0.01), particularly in young age group, which was significantly higher than that in middle-old age group (P < 0.01).
The effect of moxibustion in youth is evidently superior to that in middle-old age. Its mechanism is connected with that moxibustion can enhance the expression of erythrocyte CD58.
观察隔药饼灸对不同年龄段健康人群红细胞CD58表达的影响，探讨其在不同年龄段治疗效果的差异及其机制。
将82名健康受试者按年龄分为青年组和中老年组。采用熟地黄、山药、山茱萸等制成的药饼，对神阙（CV 8）、关元（CV 4）、足三里（ST 36）、脾俞（BL 20）、肾俞（BL 23）进行隔药饼灸。隔日治疗1次，共10次，每个穴位连续灸3壮。采用流式细胞术检测灸疗前后红细胞CD58的平均荧光强度。
灸疗后，两组红细胞CD58表达均显著高于灸疗前（均P < 0.01），尤以青年组为明显，显著高于中老年组（P < 0.01）。
艾灸对青年人群的效果明显优于中老年人群。其机制与艾灸可增强红细胞CD58的表达有关。
