Zeng Yuqing, Bi Dingyan, Yi Zhan, Lu Jianwei, Zhong Fuhua, Jiang Binfeng
Department of Orthopedics and Traumatology, Zhejiang Tongde Hospital, Hangzhou 310012, China.
College of Acupuncture-Moxibustion and Tuina, Hunan University of CM.
Zhongguo Zhen Jiu. 2017 May 12;37(5):473-476. doi: 10.13703/j.0255-2930.2017.05.005.
To explore the clinical efficacy and partial mechanism of medicinal-cake-separated moxibustion for senile osteoporosis.
Sixty cases of senile osteoporosis were randomly divided into an observation group and a control group according to the random digits table, 30 cases in each one. The two groups were both treated with basic treatment of western medicine. The acupoints included four groups:① Dazhui (GV 14), Dazhu (BL 11) and Ganshu (BL 18); ② Zhongwan (CV 12), Danzhong (CV 17) and Zusanli (ST 36); ③ Pishu (BL 20), Shenshu (BL 23) and Mingmen (GV 4); ④ Shenque (CV 8) and Guanyuan (CV 4). Each group of acupoints was selected for one treatment. The observation group was treated with medicinal-cake-separated moxibustion, and the medicinal cake was consisted of fructus psoraleae (30 g), prepared rehmannia root (30 g), atractylodes (30 g), codonopsis pilosula (30 g), epimedium herb (20 g), rhizoma curculiginis (20 g), syzygium aromaticum (5 g) and cinnamon (5 g). The control group was treated with wheat-flour-cake moxibustion. Each acupoint was treated with 5 moxa cones in the two groups. The treatment was given once every other day for six months. The symptom score, lumbar and hip bone mineral density (BMD), serum type Ⅰ procollagen amino-terminal propeptide (PINP) and serum β-type Ⅰ collagen carboxy-terminal peptide (β-CTX) were observed before and after treatment.
After treatment, the symptom score and serum β-CTX were significantly lowered (all <0.05), while the lumbar and hip BMD and serum PINP were significantly increased (all <0.05) of the two groups. After treatment, the symptom score and serum β-CTX in the observation group were significantly lower than those in the control group (both <0.05), while the lumbar and hip BMD and serum PINP in the observation group were significantly higher than those in the control group (all <0.05).
The medicinal-cake-separated moxibustion has significant efficacy for senile osteoporosis, which is superior to wheat-cake-se-parated moxibustion.
探讨隔药饼灸治疗老年性骨质疏松症的临床疗效及部分作用机制。
将60例老年性骨质疏松症患者按随机数字表法随机分为观察组和对照组，每组30例。两组均采用西医基础治疗。穴位分为四组：①大椎（GV 14）、大杼（BL 11）、肝俞（BL 18）；②中脘（CV 12）、膻中（CV 17）、足三里（ST 36）；③脾俞（BL 20）、肾俞（BL 23）、命门（GV 4）；④神阙（CV 8）、关元（CV 4）。每次选取一组穴位进行治疗。观察组采用隔药饼灸，药饼由补骨脂（30 g）、熟地黄（30 g）、白术（30 g）、党参（30 g）、淫羊藿（20 g）、仙茅（20 g）、丁香（5 g）、肉桂（5 g）组成。对照组采用隔面饼灸。两组每个穴位均灸5壮。治疗隔日1次，共6个月。观察治疗前后症状评分、腰椎和髋部骨密度（BMD）、血清Ⅰ型前胶原氨基端前肽（PINP）及血清β-Ⅰ型胶原羧基端肽（β-CTX）。
治疗后，两组症状评分及血清β-CTX均显著降低（均P<0.05），腰椎和髋部BMD及血清PINP均显著升高（均P<0.05）。治疗后，观察组症状评分及血清β-CTX显著低于对照组（均P<0.05），腰椎和髋部BMD及血清PINP显著高于对照组（均P<0.05）。
隔药饼灸治疗老年性骨质疏松症疗效显著，优于隔面饼灸。
