人唾液中存在蜡酯和角鲨烯。
Presence of wax esters and squalene in human saliva.
机构信息
Dows Institute for Dental Research, University of Iowa, Iowa City, IA 52242, USA.
出版信息
Arch Oral Biol. 2011 Jun;56(6):588-91. doi: 10.1016/j.archoralbio.2010.12.002. Epub 2011 Jan 17.
Abstract
OBJECTIVE
The purpose of this study was to determine the presence and relative composition of neutral lipids in human saliva.
DESIGN
Whole unstimulated saliva was collected from 12 subjects ranging from 21 to 29 years old. Samples were lyophilized, and lipids were extracted using chloroform-methanol. Lipids were analysed by thin-layer chromatography.
RESULTS
Human saliva contains cholesterol, fatty acids, triglycerides, wax esters, cholesterol esters and squalene. The mean total neutral lipid content was 12.1±6.3 μg/ml.
CONCLUSIONS
These lipids in human saliva closely resemble the lipids found on the skin surface. These salivary lipids are most likely produced by the sebaceous follicles in the oral mucosa and sebaceous glands associated with major salivary glands.
摘要
目的
本研究旨在确定人唾液中中性脂质的存在及其相对组成。
设计
从 12 名年龄在 21 至 29 岁的受试者中采集未经刺激的全唾液。将样本冻干，并用氯仿-甲醇提取脂质。通过薄层层析分析脂质。
结果
人唾液中含有胆固醇、脂肪酸、甘油三酯、蜡酯、胆固醇酯和角鲨烯。中性脂质的总含量平均为 12.1±6.3 μg/ml。
结论
这些人唾液中的脂质与皮肤表面发现的脂质非常相似。这些唾液脂质很可能是由口腔黏膜的皮脂腺和与大唾液腺相关的皮脂腺产生的。
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