牙买加宫内人工授精作为一种低成本的低资源地区的不孕不育治疗方法。
Intrauterine insemination in Jamaica as a low-cost subfertility treatment in a low-resource region.
机构信息
Department of Obstetrics and Gynecology, University of the West Indies, Mona, Jamaica.
出版信息
Int J Gynaecol Obstet. 2011 Mar;112(3):208-10. doi: 10.1016/j.ijgo.2010.10.017. Epub 2011 Jan 17.
OBJECTIVE
To determine the impact of intrauterine insemination on the management of subfertility in Jamaica.
METHODS
The present study was a retrospective analysis of all intrauterine insemination cycles completed from May 1, 2002, to August 31, 2005, at the University of the West Indies, Mona, Jamaica. The cycle pregnancy rate (CPR), live-birth rate (LBR), and cumulative pregnancy rate were obtained and prognostic factors were reviewed.
RESULTS
The CPR, LBR, and cumulative pregnancy rate were 10.1%, 8.8%, and 13.9%, respectively. Improved success was significantly associated with a shorter period of infertility (3.10 ± 1.43 years vs 5.22 ± 2.89 years; P = 0.01). Women younger than 40 years of age, men with increased post-preparation sperm counts, and couples undergoing 2-3 cycles had improved outcomes.
CONCLUSION
Intrauterine insemination represents a safe and cost-effective option for mild male factor infertility or unexplained infertility, especially in resource-poor regions such as the Caribbean. Repeated failed cycles identify those who would probably benefit from early intervention with in vitro fertilization.
目的
确定宫内授精对牙买加不孕症治疗的影响。
方法
本研究是对 2002 年 5 月 1 日至 2005 年 8 月 31 日在牙买加莫纳西印度群岛大学完成的所有宫内授精周期的回顾性分析。获得了周期妊娠率（CPR）、活产率（LBR）和累积妊娠率，并回顾了预测因素。
结果
CPR、LBR 和累积妊娠率分别为 10.1%、8.8%和 13.9%。不孕时间较短（3.10 ± 1.43 年 vs 5.22 ± 2.89 年；P = 0.01）与成功率显著提高相关。年龄小于 40 岁的女性、预备前精子计数增加的男性和进行 2-3 个周期的夫妇的结局得到改善。
结论
宫内授精是轻度男性因素不孕或不明原因不孕的安全且具有成本效益的选择，尤其适用于加勒比等资源匮乏地区。反复失败的周期表明，那些可能受益于早期体外受精干预的患者。
Zotero 插件