Department of Critical care Medicine, Changhua Christian Hospital, Changhua, Taiwan, ROC.
Am J Emerg Med. 2012 Jan;30(1):258.e3-5. doi: 10.1016/j.ajem.2010.10.028. Epub 2011 Jan 17.
Necrotizing fasciitis is an uncommon but life-threatening condition with a high associated mortality and morbidity. Most infections are polymicrobial, another distinct form of necrotizing fasciitis that occurred by penetrating freshwater trauma, such as fishing or wading in wet fields. Aeromonas species are responsible. The rapidity of the infectious process is similar to that of clostridial infection, but gas production is not a consistent feature. We report a patient who presented with fever, chills, and bullae on left forearm, despite antibiotics and wound debridement; the infection extend to mid humerus with a rapid onset of skin necrosis and progressive sepsis. Aeromonas schubertii fasciitis is particularly virulent. An apparent superficial cellulitis that fails to respond to standard therapy must raise suspicion of a more extensive underlying subcutaneous infection. Aggressive surgical debridement and antibiotic coverage for gram-negative rods are the essential features of treatment. Delay caused by a mistaken diagnosis of cellulitis and subsequent inadequate debridement would likely prove fatal.
坏死性筋膜炎是一种罕见但危及生命的疾病,死亡率和发病率都很高。大多数感染是多种微生物的,是一种不同类型的坏死性筋膜炎,由穿透性淡水创伤引起,如钓鱼或在湿地跋涉。产气单胞菌是病原体。感染过程的迅速性类似于梭状芽孢杆菌感染,但不产生气体是其一个不一致的特征。我们报告了一位患者,尽管使用了抗生素和清创术,但左前臂仍出现发热、寒战和水疱;感染迅速蔓延至肱中部,皮肤坏死和进行性败血病迅速发生。舒氏气单胞菌性筋膜炎特别具有毒性。明显的浅蜂窝织炎,如果对标准治疗没有反应,必须怀疑有更广泛的潜在皮下感染。积极的手术清创和针对革兰氏阴性杆菌的抗生素覆盖是治疗的关键特征。由于错误诊断为蜂窝织炎并随后清创不充分而导致的延误可能是致命的。