College of Chemistry and Material Science, Shandong Agricultural University, Taian, Shandong, PR China.
Biosens Bioelectron. 2011 Mar 15;26(7):3278-83. doi: 10.1016/j.bios.2010.12.043. Epub 2010 Dec 31.
An enzymeless biosensor was explored from Cu-Mg-Al calcined layered double hydroxide (CLDH) modified electrode in this study. The Cu-Mg-Al CLDH greatly promotes the electron transfer between H(2)O(2) and GCE, and it is exemplified toward the non-enzymatic sensing of H(2)O(2). The results indicate that the Cu-Mg-Al CLDH exhibits excellent electrocatalytic property, high sensitivity, good reproducibility, long-term stability, and fast amperometric response toward reduction of H(2)O(2), thus is promising for the future development of man-made mimics of enzyme in H(2)O(2) sensors. This work opens a way to utilize simply Cu-Mg-Al CLDH as an electron mediator to fabricate an efficient H(2)O(2) biosensor, which exhibits great potential applications in varieties of simple, robust, and easy-to-make analytical approaches in the future.
本研究探索了一种无酶生物传感器,该传感器基于 Cu-Mg-Al 水滑石(CLDH)修饰电极。Cu-Mg-Al CLDH 极大地促进了 H₂O₂和 GCE 之间的电子转移,并可用于非酶促检测 H₂O₂。结果表明,Cu-Mg-Al CLDH 具有优异的电催化性能、高灵敏度、良好的重现性、长期稳定性以及对 H₂O₂还原的快速电流响应,因此有望成为未来人工模拟酶在 H₂O₂传感器中的发展方向。这项工作为利用简单的 Cu-Mg-Al CLDH 作为电子媒介来制备高效 H₂O₂生物传感器开辟了一条途径,该传感器在未来各种简单、稳健和易于制备的分析方法中具有很大的应用潜力。