Neurosurgical Department, The Ninth People's Hospital of Shanghai Affiliated with Shanghai Jiaotong University, 639 Zizaoju Road, Shanghai, China.
J Clin Neurosci. 2011 Mar;18(3):344-6. doi: 10.1016/j.jocn.2010.07.110. Epub 2011 Jan 17.
We retrospectively reviewed the management of 49 patients with parapontine epidermoid cyst presenting with trigeminal neuralgia, emphasizing the importance of fully removing the tumor to relieve the trigeminal neuralgia. Clinical symptoms, MRI, the operative approach, and post-operative results were examined. Trigeminal neuralgia was noted in all patients. The mean duration from onset of symptoms to surgery was 18 months. Total removal was achieved in 23 patients, near-total removal in 21, and subtotal removal in five patients. However, all tumor capsule that adhered to the trigeminal nerve was completely removed. After the operation, 33 patients developed facial hypoesthesia, three complained of double vision, and two developed acute hydrocephalus. At six months of follow-up, all patients had recovered and returned to their normal lives. At 2 years of follow-up, one patient experienced pain recurrence and underwent another operation. Parapontine epidermoid cysts either encase cranial nerve (CN) V but with intact arachnoid between the capsule and the nerve, or compress and distort the nerve with tumor capsule adherent or attached to the nerve surface. Resecting the tumor capsule's attachment to CN V is critical in relieving pain, even though this method may damage the nerve.
我们回顾性分析了 49 例桥脑背侧表皮样囊肿患者的治疗方法,强调了充分切除肿瘤以缓解三叉神经痛的重要性。我们对这些患者的临床症状、MRI、手术入路和术后结果进行了检查。所有患者均有三叉神经痛。从症状出现到手术的平均时间为 18 个月。23 例患者肿瘤全切除,21 例患者近全切除,5 例患者次全切除。但所有与三叉神经粘连的肿瘤包膜均被完全切除。术后 33 例患者出现面部感觉减退,3 例患者诉复视,2 例患者发生急性脑积水。随访 6 个月时,所有患者均已恢复并回归正常生活。随访 2 年时,1 例患者出现疼痛复发,再次接受手术治疗。桥脑背侧表皮样囊肿要么包裹颅神经 V,但在包膜和神经之间有完整的蛛网膜,要么肿瘤包膜紧贴或附着在神经表面,压迫和扭曲神经。切除与颅神经 V 相连的肿瘤包膜对于缓解疼痛至关重要,尽管这种方法可能会损伤神经。