Miyasaka Y, Morii S, Tachibana S, Saito T, Ohwada T
No Shinkei Geka. 1976 May;4(5):483-8.
We have reported a case of paratrigeminal epidermoid originated in the Meckel's cave. A 30 years old man was admitted to the department of neurosurgery with chief complaints of continuous right facial pain and numbness of entire right side of the face of three years duration. The positive neurological findings were hypesthesia over the distribution of the right trigeminal nerve, absence of the right corneal reflex and nystagmus on left lateral gaze. Caloric response was absent on the right side, however the audiogram showed normal. Cerebrospinal fluid examination was within normal limit. Electromyography showed giant spike in the right masseter and temporal muscles. Radiogram of the skull revealed a bone-destroying lesion over the medial florr of the right middle fossa involving the apex of the petrous bone (Fig 1). Right carotid angiography showed straightening and forward displacement of C4- C5 portion of the carotid siphon in the lateral view, and vertebral angiography showed displacement of basilar artery to the left side, upward displacement of the right posterior cerebral and superior cerebellar artery in the frontal view (Fig. 2, 3). At the time of operation, an epidermoid was identified in the Meckel's cave and totally removed microsurgically. Small amount of the tumor extending into the posterior fossa was also removed (Fig. 4, 5, 6, 7). Postoperative course was uneventfull except for an episode of headache and high fever of short duration, suggesting the signs of meningial irritation. Two months postoperativelly patient was relived of facial pain and was discharged with sensory impairment of the right trigeminal nerve distribution. Only 11 cases of paratrigeminal epidermoid, including the cases localized in the Meckel's cave have been reported in the past literatures (Table 1). In this paper we have discussed about the symptomatology and clinical data of paratrigeminal epidermoid and compared with those of trigeminal neurinoma, and meningioma originated in the same region. We would like to emphasize that the importance of differentiating the idiopathic trigeminal neuralgia from the paratrigeminal epidermoid, if the initial symptom of this tumor were tic douloureux. The total removal of epidermoid with capsule is essential treatment following the early diagnosis, however the attempt of total removal is sometimes difficult because of the relationship between the origin, size and extension of this kind of tumor to other important brain structures. And if some of the tumor is left behind at the time of operation, cholesterin meningitis is an important complication.
我们曾报告过一例起源于 Meckel 腔的三叉神经旁表皮样囊肿。一名 30 岁男性因持续三年的右侧面部疼痛及右侧面部全侧麻木为主诉入住神经外科。神经系统阳性体征为右侧三叉神经分布区感觉减退、右侧角膜反射消失及左侧侧视时眼球震颤。右侧冷热试验无反应,但听力图显示正常。脑脊液检查正常。肌电图显示右侧咬肌和颞肌出现巨大棘波。颅骨 X 线片显示右侧中颅窝内侧底部骨质破坏病变,累及岩骨尖(图 1)。右侧颈动脉血管造影侧位片显示颈内动脉虹吸部 C4 - C5 段变直并向前移位,椎动脉血管造影正位片显示基底动脉向左移位,右侧大脑后动脉及小脑上动脉向上移位(图 2、3)。手术时,在 Meckel 腔内发现一个表皮样囊肿并通过显微手术完全切除。少量延伸至后颅窝的肿瘤也被切除(图 4、5、6、7)。术后过程顺利,仅出现过一次短暂的头痛和高热,提示有脑膜刺激征。术后两个月患者面部疼痛缓解,出院时右侧三叉神经分布区有感觉障碍。过去的文献中仅报道过 11 例三叉神经旁表皮样囊肿,包括局限于 Meckel 腔的病例(表 1)。在本文中,我们讨论了三叉神经旁表皮样囊肿的症状学和临床资料,并与起源于同一区域的三叉神经鞘瘤和脑膜瘤进行了比较。我们想强调,如果该肿瘤的初始症状为三叉神经痛,那么将特发性三叉神经痛与三叉神经旁表皮样囊肿相鉴别非常重要。完整切除带包膜的表皮样囊肿是早期诊断后的必要治疗方法,然而由于这类肿瘤的起源、大小及其向其他重要脑结构的延伸关系,有时完全切除的尝试很困难。而且如果手术时残留部分肿瘤,胆固醇性脑膜炎是一个重要的并发症。