Department of Anatomy, Biochemistry & Physiology, Institute for Biogenesis Research, John A. Burns School of Medicine, University of Hawaii at Manoa, 1960 East-West Road, Honolulu, HI 96822, USA.
Biol Reprod. 2011 May;84(5):841-3. doi: 10.1095/biolreprod.111.090951. Epub 2011 Jan 19.
In this issue, Meyer-Ficca et al. demonstrate that PARP1 and PARG regulate TOP2B mediated DNA double-strand breaks during spermiogenesis.
本期杂志中,Meyer-Ficca 等人研究表明,在精子发生过程中,PARP1 和 PARG 可调节 TOP2B 介导的 DNA 双链断裂。