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肺动脉高压:病理生理学和麻醉管理综述。

Pulmonary hypertension: a review of pathophysiology and anesthetic management.

机构信息

Ronald Regan UCLA Medical Center, Department of Anesthesiology, Division of Cardiothoracic Anesthesia, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-7403, USA.

出版信息

Am J Ther. 2012 Sep;19(5):377-83. doi: 10.1097/MJT.0b013e3181f94c02.

Abstract

Pulmonary hypertension is a condition that can result in serious complications in patients undergoing any type of anesthesia during the perioperative period. By definition, pulmonary artery hypertension is caused by a persistent rise in mean pulmonary artery pressure ≥25 mm Hg with Pulmonary capillary wedge pressure ≤ 15 mm Hg or exercise mean pulmonary artery pressure ≥35 mm Hg and pulmonary vascular resistance ≥ 3 wood unit's. The severity of the complications depends on the severity of the underlying condition, other comorbidities, and type of procedure, anesthetic technique, and anesthetic drugs. In this article, we briefly review the pulmonary vascular physiology, pathophysiology of the disease, clinical assessment and diagnosis, treatment options, and the anesthetic management of these patients.

摘要

肺动脉高压是一种在围手术期接受任何类型麻醉的患者都可能出现严重并发症的疾病。根据定义,肺动脉高压是由平均肺动脉压持续升高≥25mmHg,同时肺毛细血管楔压≤15mmHg 或运动时平均肺动脉压≥35mmHg 和肺血管阻力≥3 伍德单位引起的。并发症的严重程度取决于基础疾病的严重程度、其他合并症、手术类型、麻醉技术和麻醉药物。在本文中,我们简要回顾了肺血管生理学、疾病的病理生理学、临床评估和诊断、治疗选择以及这些患者的麻醉管理。

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