4th Department of Surgery, Medical School, University of Athens, Attikon University Hospital, Arkadias 19-21, Athens 12462, Greece.
Surg Oncol. 2011 Jun;20(2):e93-101. doi: 10.1016/j.suronc.2010.12.003. Epub 2011 Jan 19.
Mucinous cystic neoplasms (MCNs) of the pancreas represent one of the most common primary pancreatic cystic neoplasms, accounting for approximately half of these cases. MCNs are observed almost exclusively in women, and most commonly are located in the body/tail of the pancreas. In contrast to SCNs, MCNs have malignant potential. Proliferative changes (hyperplasia with or without atypia, borderline changes, non-invasive or carcinomas in-situ, and invasive carcinomas) can often be observed within the same neoplasm. Several risk factors for the presence of underlying malignancy within an MCN have recently been recognized. Cross-sectional imaging is of key importance for the diagnostic evaluation of patients with a cystic pancreatic lesion. Cyst fluid examination (cytology, biochemical/genetic analysis) is possible by using fine needle aspiration of the MCN, usually under endoscopic guidance, and may provide useful information for the differential diagnosis. Since MCNs have malignant potential, surgical resection is the treatment of choice.
胰腺黏液性囊性肿瘤（MCN）是最常见的胰腺原发性囊性肿瘤之一，约占此类病例的一半。MCN 几乎仅见于女性，且最常位于胰体/尾部。与 SCN 不同，MCN 具有恶性潜能。同一肿瘤内常可观察到增生性改变（增生伴或不伴异型性、交界性改变、非浸润性或原位癌、浸润性癌）。最近已经认识到 MCN 中存在潜在恶性的一些危险因素。对于囊性胰腺病变患者，横断面成像对诊断评估至关重要。可通过对 MCN 进行细针抽吸（通常在内镜引导下）进行囊液检查（细胞学、生化/遗传学分析），这可为鉴别诊断提供有用信息。由于 MCN 具有恶性潜能，因此手术切除是首选治疗方法。
