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[胰腺囊性肿瘤:手术治疗与治愈机会]

[Cystic neoplasms of the pancreas: surgical therapy and chances for cure].

作者信息

Schmidt-Rohlfing B, Siech M, Mattfeldt T, Schoenberg M H, Beger H G

机构信息

Chirurgische Universitätsklinik, Abteilung für Allgemeinchirurgie, Universität Ulm.

出版信息

Z Gastroenterol. 1998 Nov;36(11):939-45.

PMID:9880820
Abstract

Between 1986 and 1997 we treated 67 patients with 68 cystic tumors of the pancreas including 17 mucinous cystadenocarcinomas, four serous cystadenocarcinomas, 15 mucinous cystadenomas, 18 serous cystadenomas, ten intraductal papillary-mucinous tumors, three solid-pseudopapillary tumors, and one cystic neuroendocrine tumor. Regarding surgical therapy our results reveal a differentiated management with respect to the histological findings. While in benign tumors a local resection is adequate the cystadenocarcinomas require an extended resection. In general there is an indication for surgical therapy in all cystic tumors of the pancreas--not only in malignant neoplasias. A nonoperative management is not justified. With a mean follow-up of 35 months the prognosis of the patients with a benign cystic tumor was excellent revealing a mortality of 0% whereas survival of the patients with a cystadenocarcinoma was 67% at five years.

摘要

1986年至1997年间,我们治疗了67例患有68个胰腺囊性肿瘤的患者,其中包括17例黏液性囊腺癌、4例浆液性囊腺癌、15例黏液性囊腺瘤、18例浆液性囊腺瘤、10例导管内乳头状黏液性肿瘤、3例实性假乳头状肿瘤和1例囊性神经内分泌肿瘤。关于手术治疗,我们的结果显示根据组织学检查结果进行了差异化管理。对于良性肿瘤,局部切除就足够了,而囊腺癌则需要扩大切除。一般来说,所有胰腺囊性肿瘤都有手术治疗的指征——不仅是恶性肿瘤。非手术治疗是不合理的。平均随访35个月,良性囊性肿瘤患者的预后极佳,死亡率为0%,而囊腺癌患者的5年生存率为67%。

相似文献

1
[Cystic neoplasms of the pancreas: surgical therapy and chances for cure].[胰腺囊性肿瘤:手术治疗与治愈机会]
Z Gastroenterol. 1998 Nov;36(11):939-45.
2
Cystic pancreatic neoplasms: 12-year surgical experience.胰腺囊性肿瘤:12年手术经验
J Exp Clin Cancer Res. 2006 Jun;25(2):167-75.
3
[Cystic tumors of the pancreas].[胰腺囊性肿瘤]
Chirurg. 1996 Jul;67(7):719-24.
4
Overview of the clinical problem: facts and current issues of mucinous cystic neoplasms of the pancreas.临床问题概述:胰腺黏液性囊性肿瘤的事实与当前问题
Dig Liver Dis. 2008 Nov;40(11):837-46. doi: 10.1016/j.dld.2008.03.018. Epub 2008 May 22.
5
[Cystic tumors of the pancreas: apropos of 36 cases].[胰腺囊性肿瘤:附36例报告]
Ann Chir. 1994;48(8):697-702.
6
[Radical surgery in cystadenoma of the pancreas--long-term experiences with 35 patients].[胰腺囊腺瘤的根治性手术——35例患者的长期经验]
Langenbecks Arch Chir Suppl Kongressbd. 1998;115:1341-3.
7
Noninvasive pancreatic cystic neoplasms can be safely and effectively treated by limited pancreatectomy.非侵袭性胰腺囊性肿瘤可通过有限胰腺切除术进行安全有效的治疗。
Ann Surg Oncol. 2008 Jan;15(1):193-8. doi: 10.1245/s10434-007-9613-3. Epub 2007 Oct 2.
8
[Mucinous cystadenomas and cystadenocarcinomas of the pancreas--the pancreaticoscopy as a new device for endoscopic and histological diagnosis].[胰腺黏液性囊腺瘤和囊腺癌——胰镜作为内镜及组织学诊断的新设备]
Z Gastroenterol. 1994 Mar;32(3):165-9.
9
[Rare tumors of the pancreas].[胰腺罕见肿瘤]
Zentralbl Chir. 2003 May;128(5):429-33. doi: 10.1055/s-2003-40044.
10
Management of suspected pancreatic cystic neoplasms based on cyst size.基于囊肿大小的疑似胰腺囊性肿瘤的管理
Surgery. 2008 Oct;144(4):677-84; discussion 684-5. doi: 10.1016/j.surg.2008.06.013. Epub 2008 Aug 29.

引用本文的文献

1
Histological percutaneous diagnosis of stage IV microcystic serous cystadenocarcinoma of the pancreas.胰腺IV期微囊性浆液性囊腺癌的组织学经皮诊断
BMJ Case Rep. 2013 Jan 30;2013:bcr2012007924. doi: 10.1136/bcr-2012-007924.
2
Serous cystadenocarcinoma of the pancreas: report of a case and management reflections.胰腺浆液性囊腺癌:病例报告及治疗思考。
World J Surg Oncol. 2012 Mar 8;10:51. doi: 10.1186/1477-7819-10-51.
3
Pancreatic serous cystadenocarcinoma: a case report and review of the literature.胰腺浆液性囊腺癌:病例报告及文献复习。
J Gastrointest Surg. 2009 Oct;13(10):1864-8. doi: 10.1007/s11605-009-0926-3. Epub 2009 May 21.
4
Cystic neoplasms of the pancreas and tumor-like lesions with cystic features: a review of 418 cases and a classification proposal.胰腺囊性肿瘤及具有囊性特征的肿瘤样病变:418例病例回顾及分类建议
Virchows Arch. 2004 Aug;445(2):168-78. doi: 10.1007/s00428-004-1043-z. Epub 2004 Jun 8.