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[胰腺囊性肿瘤:手术治疗与治愈机会]

[Cystic neoplasms of the pancreas: surgical therapy and chances for cure].

作者信息

Schmidt-Rohlfing B, Siech M, Mattfeldt T, Schoenberg M H, Beger H G

机构信息

Chirurgische Universitätsklinik, Abteilung für Allgemeinchirurgie, Universität Ulm.

出版信息

Z Gastroenterol. 1998 Nov;36(11):939-45.

PMID:9880820
Abstract

Between 1986 and 1997 we treated 67 patients with 68 cystic tumors of the pancreas including 17 mucinous cystadenocarcinomas, four serous cystadenocarcinomas, 15 mucinous cystadenomas, 18 serous cystadenomas, ten intraductal papillary-mucinous tumors, three solid-pseudopapillary tumors, and one cystic neuroendocrine tumor. Regarding surgical therapy our results reveal a differentiated management with respect to the histological findings. While in benign tumors a local resection is adequate the cystadenocarcinomas require an extended resection. In general there is an indication for surgical therapy in all cystic tumors of the pancreas--not only in malignant neoplasias. A nonoperative management is not justified. With a mean follow-up of 35 months the prognosis of the patients with a benign cystic tumor was excellent revealing a mortality of 0% whereas survival of the patients with a cystadenocarcinoma was 67% at five years.

摘要

1986年至1997年间,我们治疗了67例患有68个胰腺囊性肿瘤的患者,其中包括17例黏液性囊腺癌、4例浆液性囊腺癌、15例黏液性囊腺瘤、18例浆液性囊腺瘤、10例导管内乳头状黏液性肿瘤、3例实性假乳头状肿瘤和1例囊性神经内分泌肿瘤。关于手术治疗,我们的结果显示根据组织学检查结果进行了差异化管理。对于良性肿瘤,局部切除就足够了,而囊腺癌则需要扩大切除。一般来说,所有胰腺囊性肿瘤都有手术治疗的指征——不仅是恶性肿瘤。非手术治疗是不合理的。平均随访35个月,良性囊性肿瘤患者的预后极佳,死亡率为0%,而囊腺癌患者的5年生存率为67%。

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