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评估人乳头瘤病毒(HPV)疫苗接种对马里 HPV 流行率和宫颈癌发病率的影响。

Estimating the impact of human papillomavirus (HPV) vaccination on HPV prevalence and cervical cancer incidence in Mali.

机构信息

Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.

出版信息

Clin Infect Dis. 2011 Mar 1;52(5):641-5. doi: 10.1093/cid/ciq190. Epub 2011 Jan 20.

Abstract

Human papillomavirus vaccines have potential to reduce cervical cancer incidence and mortality; however, cultural and economic barriers may hinder success in developing countries. We assessed impact of a single vaccine campaign in Mali with use of mathematical modeling. Our model shows that decreases in the prevalence of Human papillomavirus infection are proportional to achieved vaccination coverage.

摘要

人乳头瘤病毒疫苗具有降低宫颈癌发病率和死亡率的潜力;然而,文化和经济障碍可能会阻碍发展中国家的成功。我们使用数学模型评估了马里单次疫苗接种活动的影响。我们的模型表明,人乳头瘤病毒感染的流行率下降与实际接种覆盖率成正比。

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