Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Clin Infect Dis. 2011 Mar 1;52(5):641-5. doi: 10.1093/cid/ciq190. Epub 2011 Jan 20.
Human papillomavirus vaccines have potential to reduce cervical cancer incidence and mortality; however, cultural and economic barriers may hinder success in developing countries. We assessed impact of a single vaccine campaign in Mali with use of mathematical modeling. Our model shows that decreases in the prevalence of Human papillomavirus infection are proportional to achieved vaccination coverage.
人乳头瘤病毒疫苗具有降低宫颈癌发病率和死亡率的潜力;然而,文化和经济障碍可能会阻碍发展中国家的成功。我们使用数学模型评估了马里单次疫苗接种活动的影响。我们的模型表明,人乳头瘤病毒感染的流行率下降与实际接种覆盖率成正比。