From Weill Cornell Medical College; New York Presbyterian Hospital-Weill Cornell Medical Center; the Department of Pathology, New York Presbyterian Hospital-Weill Cornell Medical Center; and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York.
Obstet Gynecol. 2011 Feb;117(2 Pt 2):482-484. doi: 10.1097/AOG.0b013e3182051dd0.
Rhabdomyosarcomas, particularly those of gynecologic origin, are very rare in adults. As a result, there is little literature on the optimal staging procedure and treatment modalities for this population.
A 43-year-old woman presented with a long-standing history of menorrhagia and was subsequently diagnosed with embryonal rhabdomyosarcoma of the cervix. She underwent a total abdominal hysterectomy, bilateral salpingo-oophorectomy, lymph node dissection, omentectomy, and appendectomy, which also revealed a synchronous tubular carcinoid tumor of appendiceal origin. Plans for treatment involve adjuvant chemotherapy with vincristine, dactinomycin, and cyclophosphamide.
This case adds to the small body of literature surrounding cervical embryonal rhabdomyosarcoma in women over the age of 40 years and proposes that appendectomy be considered during surgical management.
横纹肌肉瘤，尤其是妇科来源的横纹肌肉瘤，在成年人中非常罕见。因此，针对这一人群，关于最佳分期程序和治疗方式的文献资料很少。
一位 43 岁女性因月经过多的长期病史就诊，随后被诊断为宫颈胚胎性横纹肌肉瘤。她接受了全子宫切除术、双侧输卵管卵巢切除术、淋巴结清扫术、网膜切除术和阑尾切除术，术中还发现阑尾起源的同步管状类癌肿瘤。治疗计划包括用长春新碱、放线菌素 D 和环磷酰胺进行辅助化疗。
本病例增加了 40 岁以上女性宫颈胚胎性横纹肌肉瘤的少量文献资料，并提出在手术治疗中应考虑行阑尾切除术。
