抗精神病药恶性综合征
Neuroleptic malignant syndrome.
作者信息
Reinish L W, Remick R A
出版信息
Can Fam Physician. 1988 Oct;34:2317-20.
Abstract
The neuroleptic malignant syndrome (NMS) is a potentially fatal syndrome characterized by diffuse muscular rigidity, pyrexia, sweating, cardiovascular instability, and elevated serum creatinine phosphokinase. NMS occurs in 2% of all patients exposed to neuroleptics (antipsychotic drugs). A case of successfully treated NMS is presented, and the typical symptomatic presentation, etiology, pathogenesis, and treatment options of this syndrome are described.
摘要
神经阻滞剂恶性综合征（NMS）是一种潜在致命性综合征，其特征为弥漫性肌肉强直、发热、出汗、心血管功能不稳定以及血清肌酸磷酸激酶升高。在所有使用神经阻滞剂（抗精神病药物）的患者中，NMS的发生率为2%。本文报告了一例成功治疗的NMS病例，并描述了该综合征的典型症状表现、病因、发病机制及治疗选择。
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