利用正电子发射断层扫描对霍奇金淋巴瘤进行预后评估及风险适应性治疗
Prognostication and Risk-Adapted Therapy of Hodgkin's Lymphoma Using Positron Emission Tomography.
作者信息
Kasamon Yvette L
机构信息
Department of Oncology and Medicine, Johns Hopkins University School of Medicine, 1650 Orleans Street, Baltimore, MD 21231, USA.
出版信息
Adv Hematol. 2011;2011:271595. doi: 10.1155/2011/271595. Epub 2010 Dec 22.
Abstract
The use of (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) for response assessment in lymphoma is now widespread. Prognostic information obtained from PET performed after two to three cycles of chemotherapy may guide more individualized, risk-adapted therapeutic strategies. Progress in the risk stratification of Hodgkin's lymphoma through midtreatment PET is reviewed, with a focus on management implications in newly diagnosed and relapsed disease. How to tailor treatment on the basis of the interim PET result is not yet defined but is the subject of ongoing trials.
摘要
（18）F-氟脱氧葡萄糖正电子发射断层扫描（FDG-PET）在淋巴瘤疗效评估中的应用现已广泛普及。在化疗两到三个周期后进行PET检查所获得的预后信息，可指导制定更具个体化、风险适应性的治疗策略。本文综述了通过治疗中期PET对霍奇金淋巴瘤进行风险分层的进展，重点关注新诊断和复发疾病的管理意义。如何根据中期PET结果调整治疗方案尚未明确，但仍是正在进行的试验的主题。
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