Woodward Lianne J, Clark Caron A C, Pritchard Verena E, Anderson Peter J, Inder Terrie E
Canterbury Child Development Research Group, Department of Psychology, University of Canterbury, Christchurch, New Zealand.
Dev Neuropsychol. 2011;36(1):22-41. doi: 10.1080/87565641.2011.540530.
Using prospective longitudinal data from 110 very preterm and 113 full term children, this article describes the executive functioning abilities of very preterm children at age 4, and examines relations between the extent of white matter abnormality on neonatal magnetic resonance imaging (MRI) and later executive function outcomes. Very preterm children performed less well than full term children on measures of planning ability, cognitive flexibility, selective attention, and inhibitory control. Executive impairments at age 4 were confined to preterm children with mild or moderate-severe white matter abnormalities on MRI. Findings support the importance of cerebral white matter integrity for later executive function.
本文利用110名极早产儿和113名足月儿的前瞻性纵向数据，描述了极早产儿4岁时的执行功能能力，并研究了新生儿磁共振成像（MRI）上白质异常程度与后期执行功能结果之间的关系。在计划能力、认知灵活性、选择性注意力和抑制控制方面的测量中，极早产儿的表现不如足月儿。4岁时的执行功能障碍仅限于MRI上有轻度或中度至重度白质异常的早产儿。研究结果支持脑白质完整性对后期执行功能的重要性。
