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[环甲膜上部分喉切除术与其他传统部分喉切除术治疗特定喉癌的比较]

[Supracricoid partial laryngectomy versus other traditional partial laryngectomy for selected laryngeal cancers].

作者信息

Yan Dangui, Zhang Bin, Qi Yongfa, Xu Zhengang, Tang Pingzhang, Changming An

机构信息

Department of Head and Neck Sugery, Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sicence, Beijing, 100021, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2010 Sep;24(18):828-31.

Abstract

OBJECTIVE

To compare the oncological and functional outcomes in patients undergoing supracricoid partial laryngectomy with other traditional partial laryngectomy.

METHOD

One hundred and fourteen patients treated from 1992 to 2007 were selected from all laryngeal cancer patients undergo partial laryngectomy through random match method by tumour subsite, TNM stage and age. Among them, 58 were supraglottic cancers, 56 were glottic cancers. Patients were divided into supracricoid laryngectomy group and other partial laryngectomy group. Each group includes 57 cases. We compare the 3-year and 5-year actuarial survival, local control rate and decannulation rate between two groups.

RESULT

The 3-year and 5-year actuarial survival estimate was 90% and 87% for supracricoid partial laryngectomy, 97% and 92% for other partial laryngectomy (P > 0.05); Local control rate estimate was 94.2% for supracricoid laryngectomy and 91% for other partial laryngectomy(P > 0.05); Decannulation rate was 98% for supracricoid laryngectomy and 89.5% for other partial laryngectomy(P>0. 05); The decannulation was ever lower in horizontal-vertical partial laryngectomy than supracricoid partial laryngectomy (75% versus 98%, P < 0.01).

CONCLUSION

Comparing with other partial laryngectomy, supracricoid partial laryngectomy seems to have higher decannulation rate and is a considerable choice for selected laryngeal cancer.

摘要

目的

比较环状软骨上部分喉切除术与其他传统部分喉切除术患者的肿瘤学及功能预后。

方法

从1992年至2007年接受治疗的所有喉癌患者中,通过随机匹配法,按照肿瘤亚部位、TNM分期和年龄,选取114例行部分喉切除术的患者。其中声门上癌58例,声门癌56例。将患者分为环状软骨上喉切除术组和其他部分喉切除术组。每组各57例。比较两组的3年和5年精算生存率、局部控制率及拔管率。

结果

环状软骨上部分喉切除术的3年和5年精算生存率估计分别为90%和87%,其他部分喉切除术分别为97%和92%(P>0.05);环状软骨上喉切除术的局部控制率估计为94.2%,其他部分喉切除术为91%(P>0.05);环状软骨上喉切除术的拔管率为98%,其他部分喉切除术为89.5%(P>0.05);水平垂直部分喉切除术的拔管率低于环状软骨上部分喉切除术(75%对98%,P<0.01)。

结论

与其他部分喉切除术相比,环状软骨上部分喉切除术似乎具有更高的拔管率,是部分喉癌患者的一个不错选择。

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