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经皮手术中药物洗脱支架患者及其抗凝治疗管理。

Patients with drug-eluting stents and management of their anticoagulant therapy in cutaneous surgery.

机构信息

Saint Louis University School of Medicine, Saint Louis, Missouri, USA.

出版信息

J Am Acad Dermatol. 2011 Mar;64(3):553-8. doi: 10.1016/j.jaad.2009.11.691. Epub 2011 Jan 20.

Abstract

Whether a patient has a drug-eluting stent (DES) implanted may not seem to be an immediate concern for a dermatologist. However, the clinician needs to consider a patient's risk of bleeding if a patient is to undergo a cutaneous surgical procedure. Patients with skin cancer are generally older with a higher risk of comorbidities such as cardiovascular disease with history of cardiac stent implantation. After DES placement, patients are typically on long-term dual antiplatelet therapy, which increases the risk of bleeding. However, stopping antiplatelet therapy prematurely can lead to serious thrombotic complications. Thus, when performing a dermatologic procedure in a patient with a DES, the physician must weigh the risks of bleeding complications with continuing antiplatelet therapy against the risk of thrombotic complications associated with stopping antiplatelet therapy. The aim of this review is to identify the issues for the dermatologist and the dermatologic surgeon surrounding the perioperative treatment of patients with a DES and to discuss the treatment of patients with an implanted DES.

摘要

是否为患者植入药物洗脱支架(DES)似乎不是皮肤科医生的当务之急。然而,如果患者要接受皮肤外科手术,临床医生需要考虑患者出血的风险。患有皮肤癌的患者通常年龄较大,患有心血管疾病等合并症的风险较高,且有心脏支架植入史。DES 放置后,患者通常需要长期接受双联抗血小板治疗,这会增加出血风险。然而,过早停止抗血小板治疗可能会导致严重的血栓并发症。因此,当在接受 DES 治疗的患者中进行皮肤科手术时,医生必须权衡继续抗血小板治疗的出血并发症风险与停止抗血小板治疗相关的血栓并发症风险。本综述的目的是确定围绕接受 DES 治疗的患者围手术期治疗的皮肤科医生和皮肤科外科医生的问题,并讨论接受植入 DES 的患者的治疗。

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