胎儿生长异常与早期、晚期及新生儿后期死亡：对密尔沃基 1996-2007 年出生儿的分析。
Aberrant fetal growth and early, late, and postneonatal mortality: an analysis of Milwaukee births, 1996-2007.
机构信息
Center for Urban Population Health, Milwaukee, WI, USA.
出版信息
Am J Obstet Gynecol. 2011 Mar;204(3):261.e1-261.e10. doi: 10.1016/j.ajog.2010.11.040. Epub 2011 Jan 21.
OBJECTIVE
The objective of the study was to ascertain the association between fetal growth (small- [SGA], appropriate- [AGA], and large-for-gestational-age [LGA]) and early, late, and postneonatal mortality.
STUDY DESIGN
Birth certificate data for nonanomalous singletons, delivered from 1996 to 2007, were obtained for Milwaukee residents. Multivariate logistic regression analyses, adjusted for 19 covariates, determined the association between fetal growth and mortality.
RESULTS
Among the 123,383 live births, SGA was 57% higher than LGA (11% vs 7%). The infant mortality rate for SGA was 11.0, AGA, 5.3, and LGA, 2.7/1000 live births. SGA was a significant risk factor for early (adjusted odds ratio, 2.66) and late (2.06) but not postneonatal mortality. The adjusted risk of mortality for LGA was not significantly different from AGA. Over 12 years, 3 types of mortality for aberrant fetal growth did not change significantly.
CONCLUSION
In the city of Milwaukee, aberrant fetal growth was variably associated with early, late, and postneonatal mortality.
目的
本研究旨在确定胎儿生长（小[小样儿]、适当[适于胎龄]和大[大于胎龄]）与早期、晚期和新生儿后期死亡之间的关联。
研究设计
获取了 1996 年至 2007 年密尔沃基居民的无畸形单胎出生证明数据。通过多变量逻辑回归分析，调整了 19 个协变量，确定了胎儿生长与死亡率之间的关联。
结果
在 123383 例活产儿中，SGA 比 LGA 高出 57%（11%对 7%）。SGA 的婴儿死亡率为 11.0，AGA 为 5.3，LGA 为 2.7/1000 活产儿。SGA 是早期（调整后的优势比，2.66）和晚期（2.06）但不是新生儿后期死亡的显著危险因素。LGA 的死亡调整风险与 AGA 无显著差异。在 12 年期间，3 种异常胎儿生长的死亡率没有显著变化。
结论
在密尔沃基市，胎儿生长异常与早期、晚期和新生儿后期死亡之间存在不同程度的关联。
Zotero 插件