[颅内室管膜瘤：16例回顾性研究]
[Intracranial ependymomas: retrospective study of 16 cases].
作者信息
Houjami M, Sahraoui S, Benchakroun N, Jouhadi H, Tawfiq N, Benider A
机构信息
Centre d'Oncologie, CHU Ibn Rochd, Casablanca, Maroc.
出版信息
Cancer Radiother. 2011 Apr;15(2):136-9. doi: 10.1016/j.canrad.2010.09.001. Epub 2011 Jan 21.
PURPOSE
To report the epidemiological, clinical aspects and therapeutic results of intracranial ependymomas in Morocco.
PATIENTS AND METHODS
Our retrospective study concerned 16 cases of intracranial ependymomas, treated from January 1995 to December 2002 at the radiotherapy department of Ibn Rochd Hospital of Casablanca, Morocco.
RESULTS
The average age was 15 years and complete surgery was possible in two cases. All the patients received cranial radiotherapy, combined with chemotherapy in six cases. Overall survival and progression-free survival at 5 years were respectively 50% and 31%. Eleven patients had local recurrence after an average period of 21 months. Progression-free survival at 5 years was better if complete resection: 100% vs. 28.6% in cases of incomplete resection, and depending on the histological type with 50% for classic ependymomas and 16.6% for anaplastic.
CONCLUSION
Ependymomas are rare tumors and complete resection is the standard treatment followed by postoperative radiotherapy. The place of chemotherapy remains to be defined.
目的
报告摩洛哥颅内室管膜瘤的流行病学、临床特征及治疗结果。
患者与方法
我们的回顾性研究涉及16例颅内室管膜瘤患者，于1995年1月至2002年12月在摩洛哥卡萨布兰卡伊本·罗什德医院放疗科接受治疗。
结果
平均年龄为15岁，2例患者可行完整手术。所有患者均接受了颅脑放疗，6例联合化疗。5年总生存率和无进展生存率分别为50%和31%。11例患者平均在21个月后出现局部复发。若完整切除，5年无进展生存率更佳：完整切除病例为100%，不完全切除病例为28.6%，且取决于组织学类型，经典型室管膜瘤为50%，间变型为16.6%。
结论
室管膜瘤是罕见肿瘤，完整切除是标准治疗方法，术后需放疗。化疗的作用仍有待确定。
Zotero 插件