从经氯仿处理的表皮葡萄球菌中顺序释放抗原：在一种可能疫苗中的应用。
Sequential release of antigens from chloroform-treated Staphylococcus epidermidis: application towards a possible vaccine.
作者信息
Ahmad A, Clarke S, Buchan A, Skinner G R
机构信息
Department of Medical Microbiology, Medical School, University of Birmingham, Edgbaston, UK.
出版信息
J Appl Bacteriol. 1990 Nov;69(5):676-85. doi: 10.1111/j.1365-2672.1990.tb01562.x.
This study describes the properties of two potential Staphylococcus epidermidis vaccines prepared by chloroform treatment of bacteria and release of antigen from these chloroform-treated organisms. Both vaccines were antigenic on testing with homologous hyperimmune serum and induced immune reactivity in immunized rabbits. There was protective efficacy in mice against intraperitoneal challenge by Staph. epidermidis.
本研究描述了两种潜在的表皮葡萄球菌疫苗的特性，这两种疫苗是通过用氯仿处理细菌并从这些经氯仿处理的生物体中释放抗体制备而成。在用同源超免疫血清检测时，两种疫苗均具有抗原性，并在免疫兔中诱导了免疫反应性。在小鼠中，这两种疫苗对表皮葡萄球菌腹腔内攻击具有保护效力。
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