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RB in breast cancer: differential effects in estrogen receptor-positive and estrogen receptor-negative disease.

作者信息

Musgrove Elizabeth A, Sutherland Robert L

出版信息

Cell Cycle. 2010 Dec 1;9(23):4607. doi: 10.4161/cc.9.23.13889.

DOI:10.4161/cc.9.23.13889
PMID:21260944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3233479/
Abstract
摘要

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Inhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and up-regulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced by silibinin and 1,25-dihydroxyvitamin D(3).抑制 AML 细胞中的 Cot1/Tlp2 癌基因可减少 ERK5 的激活并上调 p27Kip1，同时增强水飞蓟宾和 1,25-二羟维生素 D(3)诱导的分化和细胞周期阻滞。
Cell Cycle. 2010 Nov 15;9(22):4542-51. doi: 10.4161/cc.9.22.13790.
2
βTrCP-dependent degradation of CDC25B phosphatase at the metaphase-anaphase transition is a pre-requisite for correct mitotic exit.在有丝分裂中期-后期转换时，βTrCP 依赖性降解 CDC25B 磷酸酶是正确有丝分裂退出的前提条件。
Cell Cycle. 2010 Nov 1;9(21):4338-50. doi: 10.4161/cc.9.21.13593. Epub 2010 Nov 11.
3
The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts.miR-31 及其靶基因 SATB2 在癌症相关成纤维细胞中的作用。
Cell Cycle. 2010 Nov 1;9(21):4387-98. doi: 10.4161/cc.9.21.13674. Epub 2010 Nov 17.
4
Cis-interactions between non-coding ribosomal spacers dependent on RNAP-II separate RNAP-I and RNAP-III transcription domains.非编码核糖体间隔区之间的顺式相互作用依赖于 RNAP-II 将 RNAP-I 和 RNAP-III 转录结构域分开。
Cell Cycle. 2010 Nov 1;9(21):4328-37. doi: 10.4161/cc.9.21.13591. Epub 2010 Nov 11.
5
Rfc5p regulates alternate RFC complex functions in sister chromatid pairing reactions in budding yeast.Rfc5p 调控芽殖酵母姐妹染色单体配对反应中交替 RFC 复合物的功能。
Cell Cycle. 2010 Nov 1;9(21):4370-8. doi: 10.4161/cc.9.21.13634. Epub 2010 Nov 13.
6
Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae.通过全基因组表型筛选鉴定酿酒酵母中参与或调控 DNA 复制起始的新因子。
Cell Cycle. 2010 Nov 1;9(21):4399-410. doi: 10.4161/cc.9.21.13679. Epub 2010 Nov 19.
7
Cdc14p resets the competency of replication licensing by dephosphorylating multiple initiation proteins during mitotic exit in budding yeast.Cdc14p 通过在芽殖酵母有丝分裂末期去磷酸化多个起始蛋白来重置复制许可的能力。
J Cell Sci. 2010 Nov 15;123(Pt 22):3933-43. doi: 10.1242/jcs.075366. Epub 2010 Oct 27.
8
RB-pathway disruption in breast cancer: differential association with disease subtypes, disease-specific prognosis and therapeutic response.乳腺癌中 RB 通路的破坏：与疾病亚型、疾病特异性预后和治疗反应的不同关联。
Cell Cycle. 2010 Oct 15;9(20):4153-63. doi: 10.4161/cc.9.20.13454. Epub 2010 Oct 27.
9
Excess histone levels mediate cytotoxicity via multiple mechanisms.过量组蛋白水平通过多种机制介导细胞毒性。
Cell Cycle. 2010 Oct 15;9(20):4236-44. doi: 10.4161/cc.9.20.13636. Epub 2010 Oct 13.
10
Elevated histone expression promotes life span extension.组蛋白表达升高可促进寿命延长。
Mol Cell. 2010 Sep 10;39(5):724-35. doi: 10.1016/j.molcel.2010.08.015.