Amstislavskaia T G, Gladkikh D V, Belousova I I, Maslova L N, Kolosova N G
Zh Vyssh Nerv Deiat Im I P Pavlova. 2010 Sep-Oct;60(5):552-9.
Social and sexual behavior of males Wistar and senescence-accelerated OXYS rats was studied. The experimental model excluding direct interaction between partners showed that the exploratory activity decreased with aging in rats of both strains, but social motivation didn't change. No interstrain differences in intensity of sexual motivation in the presence of an inaccessible receptive female were observed in 4-month rats. The level of sexual motivation of 12-month Wistar rats didn't differ from that of 4-month animals. However, in 12-month OXYS males, sexual motivation was decreased as compared to both 4- and 12-month Wistar rats. The same regularities were found under conditions of direct interaction with a partner. Behavioral changes in 12-month OXYS rats were considered as genetically determinate abnormality at the initial stage of sexual behavior, i.e., sexual motivation. The results suggest the accelerated senescence of the reproductive system of OXYS rats.
对雄性Wistar大鼠和衰老加速的OXYS大鼠的社交和性行为进行了研究。排除伙伴之间直接互动的实验模型表明，两种品系大鼠的探索活动均随衰老而降低，但社交动机未发生变化。在4个月大的大鼠中，在存在无法接触的可接受雌性的情况下，未观察到品系间性动机强度的差异。12个月大的Wistar大鼠的性动机水平与4个月大的动物没有差异。然而，与4个月和12个月大的Wistar大鼠相比，12个月大的OXYS雄性大鼠的性动机降低。在与伙伴直接互动的条件下也发现了相同的规律。12个月大的OXYS大鼠的行为变化被认为是性行为初始阶段即性动机的基因决定异常。结果表明OXYS大鼠生殖系统衰老加速。
