[辐射诱导黑腹果蝇幼虫神经母细胞中双链断裂DNA水平的变化及雄性生殖细胞中致死突变的频率]
[The radiationally induced change of level of double-stranded breaks DNA in neuroblasts of larvae and frequency of lethal mutations in sex cells of males Drosophila melanogaster].
作者信息
Zaĭnullin V G, Iushkova E A, Gur'ev D V
出版信息
Radiats Biol Radioecol. 2010 Sep-Oct;50(5):523-7.
PMID:21261002
Abstract
The level of damage DNA in neyroblastes of larvae and frequency of recessive sex-linked lethal mutations of males from chronically irradiated populations Drosophila melanogaster, differing on mobile P-elements patterns, was estimated. Received results testify, that exposition in conditions a chronic gamma-radiation (absorbed radiation dose at one generation is compounds 10 mGy) result to increase of significance of parameters and change of sensitivity of cells to following of an acute irradiation in a dose of 3 Gy.
摘要
对具有不同移动P因子模式的慢性辐照黑腹果蝇群体中幼虫神经母细胞的DNA损伤水平和雄性隐性伴性致死突变频率进行了评估。所得结果表明，在慢性γ辐射条件下（一代吸收的辐射剂量为10 mGy）暴露会导致参数显著性增加以及细胞对3 Gy急性辐射敏感性的改变。
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