Englender M, Chamovitz D, Harell M
Department of Pediatric Otolaryngology, Edith Wolfson Hospital, Holon, Israel.
Otolaryngol Head Neck Surg. 1990 Dec;103(6):909-12. doi: 10.1177/019459989010300604.
A radionuclide method using Tc-99m was used to measure the nasal transit time in 43 patients, including normal smokers and nonsmokers and those with various nasal or paranasal pathologies. The technique described was slightly modified from that already in use in various centers in order to enable more precise measurement. Measurement of transit time of a droplet of Tc-99m phytate on the nasal mucosa appears to differentiate patients with immotile cilia syndrome from normal controls. A positive test, however, can occur also in smokers and in patients with other nasal and paranasal problems. The test is reproducible, cost-effective, and noninvasive, enabling the clinician to make a more appropriate selection of patients needing further investigation.
采用一种使用锝-99m的放射性核素方法，对43例患者的鼻腔通过时间进行测量，这些患者包括正常吸烟者、非吸烟者以及患有各种鼻腔或鼻窦疾病的患者。所描述的技术对各个中心已使用的技术进行了轻微修改，以便能够进行更精确的测量。测量锝-99m植酸盐液滴在鼻黏膜上的通过时间，似乎可以区分纤毛不动综合征患者与正常对照者。然而，吸烟者以及患有其他鼻腔和鼻窦问题的患者也可能出现阳性检测结果。该检测具有可重复性、成本效益高且无创，使临床医生能够更恰当地选择需要进一步检查的患者。
